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Uzumaki Santoso
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Description
Ion channels underlie a broad range of the most basic biological processes, from excitation and signaling to secretion and absorption. Like enzymes, they are diverse and ubiquitous macromolecular catalysts with high substrate specificity and subject to strong regulation. This fully revised and expanded third edition of Ion Channels of Excitable Membranes describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signaling, structural biology, and molecular biology and genomics. Ion Channels of Excitable Membranes begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ion Channels of Excitable Membranes is written to be accessible and interesting to life scientists and physical scientists of all kinds. It introduces all the concepts that a graduate student should be aware of but is also effective in advanced undergraduate courses. It has long been the recognized authoritative overview of this field used by all neuroscientists.
Let's be real: 2020 has been a nightmare. Between the political unrest and novel coronavirus (COVID-19) pandemic, it's difficult to look back on the year and find something, anything, that was a potential bright spot in an otherwise turbulent trip around the sun. Luckily, there were a few bright spots: namely, some of the excellent works of military history and analysis, fiction and non-fiction, novels and graphic novels that we've absorbed over the last year.
Here's a brief list of some of the best books we read here at Task & Purpose in the last year. Have a recommendation of your own? Send an email to ja...@taskandpurpose.Com and we'll include it in a future story.
Missionaries by Phil Klay
I loved Phil Klay’s first book, Redeployment (which won the National Book Award), so Missionaries was high on my list of must-reads when it came out in October. It took Klay six years to research and write the book, which follows four characters in Colombia who come together in the shadow of our post-9/11 wars. As Klay’s prophetic novel shows, the machinery of technology, drones, and targeted killings that was built on the Middle East battlefield will continue to grow in far-flung lands that rarely garner headlines. [Buy]
- Paul Szoldra, editor-in-chief
Battle Born: Lapis Lazuli by Max Uriarte
Written by 'Terminal Lance' creator Maximilian Uriarte, this full-length graphic novel follows a Marine infantry squad on a bloody odyssey through the mountain reaches of northern Afghanistan. The full-color comic is basically 'Conan the Barbarian' in MARPAT. [Buy]