What is the difference between MapDisto 2.0 and previous versions?

[Mathias Lorieux [MapDisto]]

MapDisto 2.0 still uses Excel and performs all 1.x features. However, it brings many improvements and new features. This paper describes MapDisto 2.0 major changes.

Briefly, the most important adds are:

(i) handling of very large genotyping datasets like the ones generated by genotyping-by-sequencing (GBS)

(ii) direct importation and conversion of Variant Call Format (VCF) files

(iii) detection of linkage, i.e. construction of linkage groups in case of segregation distortion

(iv) data imputation on VCF files using a new approach, called LB-Impute

(v) QTL detection via a new R/qtl graphical interface

Features (i) to (iv) operate through inclusion of new Java and R modules that are installed and used transparently by MapDisto.