Not exactly, but if you are willing to be creative with it, there are
some things you can do:
1) Setup one or more hidden merge vars on your list and populate those
with some sort of "key". Then when you send, make sure to always use a
segment that requires that field to be a certain value. You could even
change it occasionally to feel even better about that.
2) Change you list's forms to be advanced forms - setup the normal
subscribe form to be a placeholder page or a redirect. You may want to
do the same with other forms as well, though don't break your
unsubscribe form.
jesse