Lymphangiogenesis: Molecular Mechanisms and Future Promise

[lymphedemapeople]

Lymphangiogenesis: Molecular Mechanisms and Future Promise

Cell. 2010 Feb 1

Tammela T, Alitalo K.

Molecular/Cancer Biology Laboratory and Haartman Institute, Biomedicum
Helsinki, P.O.B. 63 (Haartmaninkatu 8), 00014 University of Helsinki,
Finland.
The growth of lymphatic vessels (lymphangiogenesis) is actively
involved in a number of pathological processes including tissue
inflammation and tumor dissemination but is insufficient in patients
suffering from lymphedema, a debilitating condition characterized by
chronic tissue edema and impaired immunity. The recent explosion of
knowledge on the molecular mechanisms governing lymphangiogenesis
provides new possibilities to treat these diseases.

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