Re: CALA Happy Hour No Aug7th
Ke Yuan
Jian Zhang, M.D.
Professor of Pathology
Endowed Chair in Immunology Research
University of Iowa Health Care Distinguished Scholar
Department of Pathology
The University of Iowa
On Wednesday, August 5, 2020, Ke Yuan <yuank...@gmail.com> wrote:
Dear CALA member,Due to the conflict of ATS 2020, we are NOT going to host a seminar this Friday, Aug 7th.Please mark your calendar for the next webinar, which will be Aug 28th,Title: Targeting CBLB as an Effective Approach to Boost TFH Responses Against Influenza A Virus InfectionPresenter:
Jian Zhang, M.D.
Professor of Pathology
Endowed Chair in Immunology Research
University of Iowa Health Care Distinguished Scholar
Department of Pathology
The University of IowaLook forward to meeting everyone on Aug 28th.CALAOn Tue, Jul 28, 2020 at 7:09 PM Ke Yuan <yuank...@gmail.com> wrote:2020 CALA Happy Friday Seminar
July 31st , 2020Zoom Link:https://arizona.zoom.us/j/97032505774 (Password: 654321)Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Title: Supraglottic Lung Microbiome Taxa and Pulmonary Abnormalities in an HIV Longitudinal CohortJin Zhou PhD
Associate Professor
Epidemiology & Biostatistics Department
University of ArizonaAbstract: Human immunodeficiency virus-1 infection (HIV) increases risk of non-infectious pulmonary complications. We hypothesize that an altered lung microbiome is associated with lung inflammation and evidence of lung disease. We examined the association between lung microbiome, lung function and pulmonary inflammation longitudinally in an HIV infected population before and after antiretroviral treatment (ART). We further characterized the dynamics of two distinct lung microbiome pneumotypes over time after starting ART. Thirty patients with a diagnosis of HIV and relatively advanced disease were followed in up to three visits for a maximum of three years after starting ART. At each visit, we performed pulmonary function test (PFT) and bronchoscopy with bronchoalveolar lavage (BAL) collection. The genus-level taxa were divided into two pneumotypes: supraglottic predominant (pneumotypeSPT) or background predominant (pneumotypeBPT) taxa. Weighted Spearman was used to identify genus-level taxa significantly correlated with lung function and inflammatory markers. Among eight genera that had significant positive correlations with inflammatory chemokine/cytokine levels in BAL (i.e., interleukin-8, inducible protein-10, monokine induced by IFN-γ, and interleukin-6), five were pneumotypeSPT. Subjects with higher SPT/BPT ratios had higher levels of inflammation. The presence of SPT taxa was associated with worse pulmonary function. Previously defined BPT and SPT microbial taxa had different effect on inflammation markers and lung function in an HIV positive population. The complex lung function-microbiome-inflammatory network suggests that lung microbiome may play a critical role in modulating lung function of HIV infected individuals.Stay safe and see you this Friday.CALAOn Fri, Jul 24, 2020 at 9:38 AM Ke Yuan <yuank...@gmail.com> wrote:2020 CALA Annual Meeting
July 24th, 2020
Join Zoom Meeting: https://arizona.zoom.us/j/97032505774 (Password: 654321)
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Agenda
10:35-10:40am: Brief Intro of CALA History by Dr. Dianhua Jiang
10:40-11:15am: CALA 2020 Keynote Talk—moderated by Dianhua Jiang从不明原因的病毒性肺炎到COVID-19
Dr. Bin Cao
Vice president and Director
Respiratory and Critical Care Medicine at the China-Japan Friendship Hospital in Beijing
11:15-11:30am: CALA Got Talent Show Part 1, hosted by Dr. Ke Yuan
11:30-11:40am: CALA 2019-2020 Activities Summary by Dr. Xiaobo Zhou
11:40-11:45am: CALA 2019-2020 Financial Report by Dr. Yin Chen
11:45-11:50am: CALA Members update (6/2019-7/2020) by Dr. Zhiyu Dai
11:50-12pm: CALA Got Talent Show Part 2, hosted by Dr. Ke Yuan
12pm: Closing remarks by Dr. Xiaobo ZhouStay safe and see you soon.CALAOn Tue, Jul 21, 2020 at 4:44 PM 'Juan Hou' via LungInterestGroup <lunginterestgroup@googlegroups.com> wrote:Wow, such a packed agenda and seems going to be fun and informative!Thanks to the CALA committee for your effort to put all these together!Looking forwards to our annual meeting,JuanOn Tue, Jul 21, 2020 at 1:19 PM Ke Yuan <yuank...@gmail.com> wrote:2020 CALA Annual Meeting
July 24th, 2020
Join Zoom Meeting: https://arizona.zoom.us/j/97032505774 (Password: 654321)
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Agenda
10:35-10:40am: Brief Intro of CALA History by Dr. Dianhua Jiang
10:40-11:15am: CALA 2020 Keynote Talk—moderated by Dianhua Jiang从不明原因的病毒性肺炎到COVID-19
Dr. Bin Cao
Vice president and Director
Respiratory and Critical Care Medicine at the China-Japan Friendship Hospital in Beijing
11:15-11:30am: CALA Got Talent Show Part 1, hosted by Dr. Ke Yuan
11:30-11:40am: CALA 2019-2020 Activities Summary by Dr. Xiaobo Zhou
11:40-11:45am: CALA 2019-2020 Financial Report by Dr. Yin Chen
11:45-11:50am: CALA Members update (6/2019-7/2020) by Dr. Zhiyu Dai
11:50-12pm: CALA Got Talent Show Part 2, hosted by Dr. Ke Yuan
12pm: Closing remarks by Dr. Xiaobo ZhouStay safe and see you this Friday.CALA--On Sun, Jul 19, 2020 at 2:28 PM Ke Yuan <yuank...@gmail.com> wrote:1. CALL FOR INPUTDear Cala Members,We are going to have a CALA annual party on July 24th. We would like to recognize the members' achievements in the past year. Please take a few minutes to fill the survey by July 22. Thanks.https://forms.gle/7rCvXV4XyiCfPNNP6 Or you can reply to my email for these questions:
1. Did you get a promotion or move to a new institute in the past year? Please let us know what position and what institute.
2. Were you awarded a new grant or award? Please let us know the grant title, PI, funding agent and period.
3. Do you have any recent publications to share with our community? Please let us know the PMID or a link to track.
4. Do you have any news to share with our community? We would like to celebrate with you.
2. CALL FOR TALENT
各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！ 报名截止7月23日请和Ke积极报名: yuank...@gmail.com多谢大家对CALA的支持On Thu, Jul 16, 2020 at 2:21 PM Ke Yuan <yuank...@gmail.com> wrote:2020 CALA Happy Friday SeminarJuly 17h 2020Zoom Link:https://arizona.zoom.us/j/97032505774 (Password: 654321)Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pmTitle: Zinc Metabolic Defect of Aging Alveolar Progenitors in IPF
Dr. Carol Jiurong LiangAssistant professor
Cedars-Sinai Medical Center
Abstract: Idiopathic pulmonary fibrosis (IPF) is a fatal form of interstitial lung disease and aging has been identified as a risk factor to the disease. We recently reported that there was a significant loss of alveolar progenitors (AEC2s) in the lungs of patients with IPF. In our current study, we performed single cell RNA-seq of AEC2s from patients with IPF and healthy donors as well as AEC2s from old and young mouse lungs with bleomycin injury. We identified a defect of zinc metabolism in AEC2s from IPF lungs and bleomycin-injured old mouse lungs. We further demonstrated that a specific zinc transporter ZIP8 is associated with AEC2 renewal through sirtuin signaling in aging and in IPF. Targeted deletion of Zip8 in murine AEC2 compartment leads to reduced AEC2 renewal capacity, and impaired AEC2 recovery after bleomycin injury. In summary, we have identified novel metabolic defects of AEC2s during aging and in IPF which contribute to the pathogenesis of lung fibrosis. Therapeutic strategies to restore critical components of these metabolic programs could improve AEC2 progenitor activity and mitigate ongoing fibrogenesis.Stay safe and see you tomorrow,CALAOn Wed, Jul 15, 2020 at 9:36 PM Ke Yuan <yuank...@gmail.com> wrote:1. CALL FOR INPUTDear Cala Members,We are going to have a CALA annual party on July 24th. We would like to recognize the members' achievements in the past year. Please take a few minutes to fill the survey by July 22. Thanks.https://forms.gle/7rCvXV4XyiCfPNNP6 Or you can reply to my email for these questions:
1. Did you get a promotion or move to a new institute in the past year? Please let us know what position and what institute.
2. Were you awarded a new grant or award? Please let us know the grant title, PI, funding agent and period.
3. Do you have any recent publications to share with our community? Please let us know the PMID or a link to track.
4. Do you have any news to share with our community? We would like to celebrate with you.
2. CALL FOR TALENT
各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！ 报名截止7月23日请和Ke积极报名: yuank...@gmail.com多谢大家对CALA的支持
On Sat, Jul 11, 2020 at 2:28 PM Ke Yuan <yuank...@gmail.com> wrote:CALL FOR TALENT各位朋友，CALA打算在7月24日美东时间10:30am举办CALA Summer Party，现在请各位成员积极报名CALA Talent Show，展示自己学术外的风采，一站成名的好机会！欢迎唱歌，跳舞和其他各类才艺表演，每个节目2-3分钟，也可多人在线表演！ 报名截止7月23日请和Ke积极报名: yuank...@gmail.com多谢大家对CALA的支持On Fri, Jul 10, 2020 at 7:35 AM Ke Yuan <yuank...@gmail.com> wrote:Please use this linkhttps://arizona.zoom.us/j/97032505774 (Password: 654321)On Fri, Jul 10, 2020 at 10:34 AM Beiyun Zhou <bz...@usc.edu> wrote:--Got in, thanks!
From: lunginterestgroup@googlegroups.com <lunginterestgroup@googlegroups.com> On Behalf Of Xiaobo Zhou
Sent: Friday, July 10, 2020 7:33 AM
To: lunginterestgroup@googlegroups.com
Subject: Re: CALA Happy Hour
You ca use this link
https://arizona.zoom.us/j/97032505774 (Password: 654321)
On Jul 10, 2020, at 10:30 AM, Beiyun Zhou <bz...@usc.edu> wrote:
I can not log in, It says the meeting ID is not valid.
From: lunginterestgroup@googlegroups.com <lunginterestgroup@googlegroups.com> On Behalf Of Ke Yuan
Sent: Friday, July 10, 2020 6:22 AM
To: lunginterestgroup@googlegroups.com
Subject: Re: CALA Happy Hour
2020 CALA Happy Friday Seminar
July 10th
Join Zoom Meeting:
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Stem Cell Approach to Small Cell Lung Cancer and COVID-19
Huanhuan Joyce Chen PharmD. PhD.
Assistant Professor
University of Chicago
ABSTRACT: Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop models for studying mechanisms that initiate and progress carcinogenesis, focusing initially on Small Cell Lung Cancer (SCLC), the most aggressive type of lung cancer. My currently developed cell culture models based on directed differentiation of human pluripotent stem cells (hPSC) reveal why certain constellations of genetic changes drive carcinogenesis in specialized human cell lineages. These tractable experimental systems enable studying cancer in great depth, using genetically defined human cells that can be characterized at the single cell level. I will also describe our recent work in studying COVID-19 using the cells derived from hPSCs.
Dr. Chen graduated with PhD at Cornell University, and did post-doctoral training with Dr. Harold Varmus at Weill Cornell Medicine. She joins University of Chicago as assistant professor in 2020 as a K99/R00 awardee and has many papers published in Nature Biotech, Nature Med, Cell Stem Cell, JEM and JCI etc.
Stay safe and see you soon.
CALA
On Tue, Jul 7, 2020 at 6:22 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
July 7th
Join Zoom Meeting:
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Stem Cell Approach to Small Cell Lung Cancer and COVID-19
Huanhuan Joyce Chen PharmD. PhD.
Assistant Professor
University of Chicago
ABSTRACT: Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop models for studying mechanisms that initiate and progress carcinogenesis, focusing initially on Small Cell Lung Cancer (SCLC), the most aggressive type of lung cancer. My currently developed cell culture models based on directed differentiation of human pluripotent stem cells (hPSC) reveal why certain constellations of genetic changes drive carcinogenesis in specialized human cell lineages. These tractable experimental systems enable studying cancer in great depth, using genetically defined human cells that can be characterized at the single cell level. I will also describe our recent work in studying COVID-19 using the cells derived from hPSCs.
Dr. Chen graduated with PhD at Cornell University, and did post-doctoral training with Dr. Harold Varmus at Weill Cornell Medicine. She joins University of Chicago as assistant professor in 2020 as a K99/R00 awardee and has many papers published in Nature Biotech, Nature Med, Cell Stem Cell, JEM and JCI etc.
Stay safe and see you this Friday.
CALA
On Tue, Jun 30, 2020 at 2:17 PM Ke Yuan <yuank...@gmail.com> wrote:
Dear CALA members,
We will not have a webinar this Friday due to the University Holiday (Dr. Carol Jiang's talk will be July 17th). We will resume on July 10th.
Happy July 4th everyone!
Stay Safe.
CALA
On Thu, Jun 25, 2020 at 5:02 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
June 26th, 2020
(Please note the Zoom Link change)
Join Zoom Meeting:
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
The driving force of alveolar development, regeneration, and fibrosis
Dr. Nan Tang. M.D, Ph.D.
Associate Investigator,
National Institute of Biological Sciences
The coordinated influences of both mechanical forces and growth factors during tissue development and regeneration is extremely important. With an integrated combination of mouse genetics, live imaging, lineage tracing, and quantitative cell biology, we demonstrate that alveolar development and regeneration are controlled by both mechanical forces and a local growth factor.
We have also established a direct mechanistic link between impaired alveolar regeneration, mechanical tension, and progressive lung fibrosis.
Dr. Tang obtained her Ph.D from UCSD, followed by a post-doctoral training at UCSF. She joined NIBS faculty in 2012 and has numerous high-impact publications ever since in Lancet, Cell , Dev Cell and PNAS et al.
Stay safe and see you this Friday.
CALA
On Fri, Jun 19, 2020 at 9:49 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
June 19th, 2020
(Please note the Zoom Link change)
Join Zoom Meeting:
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Lung injury and fibrosis from the metabolic viewpoint
Dr. Gang Liu. M.D, Ph.D.
Professor University of Alabama
Abstract:
The role of cellular metabolism in pulmonary diseases has been increasingly recognized in recent years. In this presentation, Dr. Liu will guide you through how glycolysis, glutaminolysis and de novo amino acid synthesis regulate lung injury and fibrosis. Dr. Liu is a Professor and Principal Investigator at the Division of Pulmonary, Allergy and Critical Care Medicine, The University of Alabama at Birmingham (UAB). Dr. Liu went to Wuhan University for his Ph.D. degree, followed by postdoctoral training in Cell Biology at Medical College of Georgia and UAB. He joined UAB faculty in 2006. Dr. Liu's laboratory is currently supported by grants from NIH and DoD.
Stay safe and see you soon.
CALA
On Tue, Jun 16, 2020 at 6:20 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
June 19th, 2020
(Please note the change of Zoom link)
Join Zoom Meeting:
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Lung injury and fibrosis from the metabolic viewpoint
Dr. Gang Liu. M.D, Ph.D.
Professor University of Alabama
Abstract:
The role of cellular metabolism in pulmonary diseases has been increasingly recognized in recent years. In this presentation, Dr. Liu will guide you through how glycolysis, glutaminolysis and de novo amino acid synthesis regulate lung injury and fibrosis. Dr. Liu is a Professor and Principal Investigator at the Division of Pulmonary, Allergy and Critical Care Medicine, The University of Alabama at Birmingham (UAB). Dr. Liu went to Wuhan University for his Ph.D. degree, followed by postdoctoral training in Cell Biology at Medical College of Georgia and UAB. He joined UAB faculty in 2006. Dr. Liu's laboratory is currently supported by grants from NIH and DoD.
Stay safe and see you all this Friday.
CALA
On Thu, Jun 11, 2020 at 10:07 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
June 12th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Multi-omics Approach to Childhood Asthma
Dr. Wei Chen
Associate Professor University of Pittsburgh
Abstract:
Athma is the most common chronic respiratory disease in children. Despite the success of genome-wide association studies, reported asthma-susceptibility loci can explained only ~3.5% of asthma heritability, supporting a strong contribution of environmental exposures to asthma causation. In this talk, Dr. Chen will describe recent advances of large-scale omics studies of asthma and relevant phenotypes including whole-genome transcriptomic and epigenetic studies. He will discuss how bioinformatic and statistical tools can help provide insight of asthma biology and prioritize candidate genes for downstream functional experiments. Dr. Chen received BS in Mathematics from Nanjing University and PhD in Biostatistics from the University of Michigan. Dr. Chen’s research focuses on developing statistical and computational methods for analyzing highthroughput genomics data. He has served as PI on multiple NIH grants and published over 100 peer reviewed papers in Nat Genet, Nat Comm, Nat Mach Intell, Lancet Respir Med, PNAS, AJRCCM, JACI, and ERJ.
Stay safe and hope to see you all this Friday.
CALA
On Thu, Jun 4, 2020 at 8:46 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
June 5th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Novel Mechanisms and Targets in Pulmonary Arterial Hypertension
Dr. Zhiyu Dai
Assistant Professor University of Arizona
Abstract: Pulmonary artery hypertension (PAH) is characterized by progressive increase in pulmonary vascular resistance and obliterative pulmonary vascular remodeling that results in right heart hypertrophy and failure and premature death. Recently, we have reported the first mouse model of PAH [Egln1Tie2Cre mice] with progressive obliterative vascular remodeling including vascular occlusion and plexiform-like lesion and right heart failure, which recapitulates many features of clinical PAH. Using this unique model, we defined several novel molecular and cellular pathways(including smooth muscle cell hyperproliferation, augmentation of nitrative stress, dysregulation of lipid metabolism) that mediate the obliterative vascular remodeling of PAH, and identified several therapeutic targets (HIF-2a, FoxM1) that potentially treat the patients with PAH. Dr. Dai graduated from Sun Yat-sen University, China, and completed his postdoctoral training at University of Illinois at Chicago and Northwestern University. The lab is funded by NHLBI Pathway to Independence Award (Parent K99/R00) and ATS Foundation Research Program.
Stay safe and hope to see you all tomorrow.
CALA
On Thu, May 28, 2020 at 2:10 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 29th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Title: Generation of a three-dimensional lung organoid from human pluripotent stem cells and its applications
Dr. Ya-Wen Chen
Assistant Professor
University of Southern California
Abstract:
Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D) would allow deeper insight into human development, as well as the development of innovative strategies for disease modeling, drug discovery and regenerative medicine. In this talk, she will show how she systematically differentiates hPSCs to lung organoids and their applications to study human lung development, diseases, and regenerative medicine. Dr Chen’s research works were published in Nature Cell Biology and Protocol Exchange in 2017. Dr. Chen had post-doc training with Dr. Hans-Willem Snoeck in Columbia University, a leader in the stem cell biology field. She started her own independent lab last year in the University of Southern California.
Stay safe and hope to see you all tomorrow.
CALA
On Mon, May 25, 2020 at 4:19 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 29th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Title: Generation of a three-dimensional lung organoid from human pluripotent stem cells and its applications
Dr. Ya-Wen Chen Assistant Professor
University of Southern California
Abstract:
Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D) would allow deeper insight into human development, as well as the development of innovative strategies for disease modeling, drug discovery and regenerative medicine. In this talk, she will show how she systematically differentiates hPSCs to lung organoids and their applications to study human lung development, diseases, and regenerative medicine. Dr Chen’s research works were published in Nature Cell Biology and Protocol Exchange in 2017. Dr. Chen had post-doc training with Dr. Hans-Willem Snoeck in Columbia University, a leader in the stem cell biology field. She started her own independent lab last year in the University of Southern California.
Stay safe and hope to see you all this Friday.
CALA
On Thu, May 21, 2020 at 11:05 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 22nd, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Interaction between alveolar epithelial stem cells and niches during lung repair
Dr. Yuru Liu
Associate Professor University of Illinois at Chicago
Abstract: Type II alveolar epithelial cells are described as facultative stem cells based on their ability to proliferate and differentiate into type I cells. However, the signals sent by surrounding niches that activate the stem cell phenotype of type II cells during alveolar repair remain unclear. Using combinatorial approaches including mouse genetic lineage tracing analysis, tissue specific inducible gene targeting techniques, and 2D and 3D in vitro culture, we will demonstrate importance of Notch and YAP pathways regulating cell-cell communication and alveolar repair. Dr. Liu is an associate professor in Department of Pharmacology, University of Illinois at Chicago. Her research is focused on lung injury and repair, especially alveolar repair mediated by type II cells. Her group have used mouse lung injury models to define sub-population of type II cells for the progenitor cell function.
Stay safe and hope to see all of you tomorrow.
CALA
On Mon, May 18, 2020 at 7:00 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 22nd, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Interaction between alveolar epithelial stem cells and niches during lung repair
Dr. Yuru Liu
Associate Professor University of Illinois at Chicago
Abstract: Type II alveolar epithelial cells are described as facultative stem cells based on their ability to proliferate and differentiate into type I cells. However, the signals sent by surrounding niches that activate the stem cell phenotype of type II cells during alveolar repair remain unclear. Using combinatorial approaches including mouse genetic lineage tracing analysis, tissue specific inducible gene targeting techniques, and 2D and 3D in vitro culture, we will demonstrate importance of Notch and YAP pathways regulating cell-cell communication and alveolar repair. Dr. Liu is an associate professor in Department of Pharmacology, University of Illinois at Chicago. Her research is focused on lung injury and repair, especially alveolar repair mediated by type II cells. Her group have used mouse lung injury models to define sub-population of type II cells for the progenitor cell function.
Stay safe and hope to see all of you this Friday.
CALA
On Thu, May 14, 2020 at 3:03 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 15th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Respiratory viral infection: from acute morbidity to chronic sequelae.
Dr. Jie Sun
Associate Professor
Mayo Clinic
Acute respiratory viral infections including influenza and SARS-CoV2 infections impose great challenges to the public health. The disease pathogenesis associated with respiratory viral infections results from a combination of the deleterious effects of virus replication and the host innate and adaptive immune responses associated with control and, ultimately, clearance of virus.
Dr. Jie Sun is an associate professor in the Departments of Medicine and Immunology at the Mayo Clinic Alix School of Medicine. He has been reviewers for many Immunology and Pulmonary
Medicine journals, and served as standing or ad hoc members on a number of NIH or DoD grant review panels. The primary research goals of Dr. Jie Sun are to develop novel ideas and methods
for the induction of strong antiviral immunity, while minimizing collateral tissue damage and the development of chronic lung sequelae following respiratory viral infections.
Stay safe and hope to see all of you this Friday.
CALA
On Fri, May 8, 2020 at 3:06 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 15th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Respiratory viral infection: from acute morbidity to chronic sequelae.
Dr. Jie Sun
Associate Professor
Mayo Clinic
Acute respiratory viral infections including influenza and SARS-CoV2 infections impose great challenges to the public health. The disease pathogenesis associated with respiratory viral infections results from a combination of the deleterious effects of virus replication and the host innate and adaptive immune responses associated with control and, ultimately, clearance of virus.
Dr. Jie Sun is an associate professor in the Departments of Medicine and Immunology at the Mayo Clinic Alix School of Medicine. He has been reviewers for many Immunology and Pulmonary
Medicine journals, and served as standing or ad hoc members on a number of NIH or DoD grant review panels. The primary research goals of Dr. Jie Sun are to develop novel ideas and methods
for the induction of strong antiviral immunity, while minimizing collateral tissue damage and the development of chronic lung sequelae following respiratory viral infections.
Stay safe and hope to see all of you next Friday.
CALA
On Thu, May 7, 2020 at 10:08 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 8th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Host microenviroment associated antibiotic resistance and novel antimicrobial development
Dr. Peter Di
Associate Professor, University of Pittsburg
Multi-drug resistant (MDR) bacterial infection has substantially increased in recent years and causes enormous concerns to public health. This talk will focus on the antibiotic resistance mechanisms and how host-pathogen interactions also contribute to the development of drug resistance. Novel antimicrobials with lower toxicity, polymyxin E will be presented. Dr. Peter Di has long standing interest in investigating the effects of environmental exposure including pathogenic microorganisms and toxic chemicals on the pathogenesis of pulmonary diseases. He has reviewed manuscripts for more than 60 different journals and grant applications for multiple funding agencies including more than 20 times of NIH study sections.
Stay safe and hope to see all of you this Friday.
CALA
On Wed, Apr 29, 2020 at 4:13 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
May 1st, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:00 am; PST: 7:00 am; Beijing time: 10:00 pm NOTE: TIME CHANGES TO 10AM
Check the enclosed flyer and Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform
Identification of the lymphangioleiomyomatosis cell and its uterine origin
Dr. Yan Xu
Professor, Cincinnati Children’s Hospital
10:00-10:45 am EST
Every Scar Tells a Story: Current Understanding and Critical Issues of Lung Fibrosis
Dr. Dianhua Jiang
Professor, Cedars Sinai Medical Center
10:45-11:30 am EST
Stay safe and hope to see all of you this Friday.
CALA
On Thu, Apr 23, 2020 at 3:01 PM Ke Yuan <yuank...@gmail.com> wrote:
Mark your calendar for tomorrow morning "2020 CALA Happy Friday Seminar"
April 24th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pmCheck the enclosed flyer.
Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform
10:30-11:00 am EST
Cigarette smoke-initiated autoimmunity in COPD: mechanisms and applications
Dr. Zhihua Chen
Professor, Zhejiang University
10:30-11:00 am ESTMolecular Insights into COPD learned from GWAS
Dr. Xiaobo Zhou
Assistant Professor, Harvard University
Stay safe and hope to see all of you tomorrow.
CALA
On Tue, Apr 21, 2020 at 9:13 AM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
April 24th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pmCheck the enclosed flyer.
Please sign up for future speakers here: https://docs.google.com/forms/d/e/1FAIpQLSda6ov0TATEozIHoCcqi1s9ewaVddy46J-0r8q3-kTEfaQeOw/viewform
10:30-11:00 am EST
Cigarette smoke-initiated autoimmunity in COPD: mechanisms and applications
Dr. Zhihua Chen
Professor, Zhejiang University
10:30-11:00 am ESTMolecular Insights into COPD learned from GWAS
Dr. Xiaobo Zhou
Assistant Professor, Harvard University
Stay safe and hope to see all of you soon.
CALA
On Thu, Apr 16, 2020 at 1:45 PM Ke Yuan <yuank...@gmail.com> wrote:
2020 CALA Happy Friday Seminar
April 17th, 2020
Join Zoom Meeting: https://zoom.us/join
Meeting ID: 998-9099-1991
Password: 397500
Time: EST 10:30 am; PST: 7:30 am; Beijing time: 10:30 pm
Mitochondria and NLRP3 inflammasome in cigarette smoke associated with acute lung injury/ARDSDr. Qing Lu, Associate Professor, Brown University
Lab research focus and relevance to COVID-19
Dr. Jianwen Que, Associate Professor, Columbia University
See the enclosed flyer.
Stay safe and hope to see all of you soon.
CALA
On Tue, Apr 14, 2020 at 4:23 PM Ke Yuan <yuank...@gmail.com> wrote:
Dear members:
Thanks, everyone for joining our online brainstorm forum on COVID-19 today. Its a great turnout and heated discussion on this hot topic. With this great momentum, we have decided to start our weekly CALA online seminar on each Friday at 10:30 am-11:30am EST(7:30am PST, 10:30pm China time). Two speakers per week for 20 min each+ 10minQ&A. We promise to finish in one hour.
Topics are flexible, arranging from each lab's own research to share your scientific stories with the group or seek more complementary skillsets for collaborations( or anything you want to discuss, such as COVID-19, or even your daily life story)
Please sign up your name as speakers by following time slots:
Thanks for your participation.
CALA
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JUAN HOU PhD
SENIOR SCIENTIST
RESEARCH & DEVELOPMENT
VANCOUVER, BC CANADA
T. 604 675 7701 • 1 800 667 0322 F. 604 877 0704 • 1 800 567 2899 E. JUAN.HOU@STEMCELL.COM W. WWW.STEMCELL.COMCONNECT WITH STEMCELL:
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