My only comment would be that the manifold pumps would normally be switched by the motorized valves to. However to do this without all the pumps always coming on you would need to use a confection unit.
Tbh I've been on too many jobs where they have tried to do what you are doing and the have been all sorts of problems because they didn't use one of these.https://www.heatmiser.com/en/central-wiring-centres/
They mean that everything turns on in the right order, there are no feedback loops and it all works as it should
Btw companies like heatmiser have a free design service (country dependant) and will tell you exactly how much pipe you need etc
Also I think you are supposed to have the 2-port valves control the boiler firing i.e. only when there is somewhere for the heat to go like a manifold or cylinder will the boiler fire. If you find the Honeywell s-plan schematic it should be clear. Called Boiler interlock. Loxone relay open 2-port, when open its microswitch allows 230v to the boiler switched live and manifold pump.