I almost hate to broach this subject, but it's an important consideration for future planning. In reference the posts below, what thought have you put into a fallback in the case Loxone becomes unavailable or otherwise become suitable for your project*?
https://groups.google.com/d/msg/loxone-english/xLJg2N2ew0Q/Ykiw3d9JCAAJ
https://groups.google.com/d/msg/loxone-english/fBz1w4Jexdo/38sW7xVzBQAJ
Using low voltage switching and home running lighting, it's not going to be practical to go back to traditional branch circuits. My case, I'm thinking worst case relays and/or adapting a commercial PLC (which was my first concept before finding Loxone). Looks like a Vantage or Centralite system might also work, though Vantage is dealer only so it's not particularly appealing to me. *I don't plan to sell my house, but I could see this being a major issue if I ever did need to sell.