BTW, the method of hand calculating this is solving simultaneous equations.
beyond three points would really require matrix methods that should really be done by a computer.
Example of solving for the three point:
y = ax^2+bx+c
(1,2)
(2,3)
(4,2)
You plug in the three points for x and y and get three equations with a,b, and c as your unknowns and you solve the system. Not easy but doable. When you go to 6 points and you're solving for 6 coefficients with 6 equations nobody does that by hand and that's only an order 5 polynomial. Imagine a statistical data set of 100 points! Also, sometimes it's impossible to have a fit, if two points have the same x value and different y vaules because then it's not a function.