Appropriate statistical test for LD Score enrichments

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Gloria Novikova

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Apr 17, 2018, 4:26:24 PM4/17/18
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Hello!

I am running stratified LD Score regression on various annotations and getting enrichments for each of them. To be clear, I am running separate models for each annotation. What would be an appropriate statistical test to test if two enrichments are significantly different or not? I cannot really use the standard error and z-score, because I am not sure if the underlying distribution is normal.

Thanks a lot for your help!

Gloria

Kaitlyn Price

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Aug 6, 2019, 7:18:06 PM8/6/19
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Hi, 

Did you ever figure out the answer to this question? I would like to convert my LD partition coefficients (z-scores) to p-values and I do not know how to do this.

Kaitlyn
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