I agree that there are some limitations with the mesher and for those cases you will need actual geometrical simplifications. But from our own experience I just wanted to share that our team has done hundreds of Therm calculations and we haven't really had situation where we needed to make considerable simplifications in geometry or shorten the flanking elements while doing ISO compliance calculations. Even for slab-on-ground-to-window-sill junctions where the floor layers adjacent to fully detailed window frame are extended up to 4 meters and soil volume up to 20 meters down and outwards. Typically we have utilized 8 / 2% / 10 combination for "QT mesh parameter" / "Maximum Error" / "Maximum iterations", but for very difficult junction we have found a solution with 7 / 5% / 15 easily within ISO accuracy limits.
I have faced a few impossible meshing situations while trying to model the full cross section of entire building just for fun, but hey it is really outside "normal" usage scenario :) .
Anyway, happy new year and happy modeling with Therm. All the best,