mediation analysis involving both parallel and serial moderators

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Marion Bailhache

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Apr 24, 2026, 10:38:24 AM (2 days ago) Apr 24

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Hello,

I am running a mediation analysis involving both parallel and serial moderators (see figure and code). The first moderator is in series with 4 moderators in parallel.

Is it possible to correctly estimate the direct and indirect effects using lavaan?

Thank you

Marion

Code:

mediation <- '

Moderator1 ~ a*categoryB + b*categoryC + c*categoryD + d*categoryE

SubscaleM2_1~ e*categoryB + f*categoryC + g*categoryD + h*categoryE + u*Moderator1

SubscaleM2_2~ i*categoryB + j*categoryC + k*categoryD + l*categoryE + v*Moderator1

SubscaleM2_3~ m*categoryB + n*categoryC + o*categoryD + p*categoryE + w*Moderator1

SubscaleM2_4~ q*categoryB + r*categoryC + s*categoryD + t*categoryE + y*Moderator1

SuscaleO_1 ~ d1*categoryB + d2*categoryC + d3*categoryD + d4*categoryE + d5*SubscaleM2_1 + d6*SubscaleM2_2 + d7*SubscaleM2_3 + d8*SubscaleM2_4 + Covariate1 + Covariate2 + Covariate3

SuscaleO_2 ~ d9*categoryB + d10*categoryC + d11*categoryD + d12*categoryE + d13*SubscaleM2_1 + d14*SubscaleM2_2 + d15*SubscaleM2_3 + d16*SubscaleM2_4 + Covariate1 + Covariate2 + Covariate3

SuscaleO_3 ~ d17*categoryB + d18*categoryC + d19*categoryD + d20*categoryE + d21*SubscaleM2_1 + d22*SubscaleM2_2 + d23*SubscaleM2_3 + d24*SubscaleM2_4 + Covariate1 + Covariate2 + Covariate3

SuscaleO_4 ~ d25*categoryB + d26*categoryC + d27*categoryD + d28*categoryE + d29*SubscaleM2_1 + d30*SubscaleM2_2 + d31*SubscaleM2_3 + d32*SubscaleM2_4 + Covariate1 + Covariate2 + Covariate3

SuscaleO_5 ~ d33*categoryB + d34*categoryC + d35*categoryD + d36*categoryE + d37*SubscaleM2_1 + d38*SubscaleM2_2 + d39*SubscaleM2_3 + d30*SubscaleM2_4 + Covariate1 + Covariate2 + Covariate3

SubscaleM2_1 ~~ SubscaleM2_2

SubscaleM2_1 ~~ SubscaleM2_3

SubscaleM2_1 ~~ SubscaleM2_4

SubscaleM2_2 ~~ SubscaleM2_3

SubscaleM2_2 ~~ SubscaleM2_4

SubscaleM2_3 ~~ SubscaleM2_4

SubscaleO_1 ~~ SubscaleO_2

SubscaleO_1 ~~ SubscaleO_3

SubscaleO_1 ~~ SubscaleO_4

SubscaleO_1 ~~ SubscaleO_5

SubscaleO_2 ~~ SubscaleO_3

SubscaleO_2 ~~ SubscaleO_4

SubscaleO_2 ~~ SubscaleO_5

SubscaleO_3 ~~ SubscaleO_4

SubscaleO_3 ~~ SubscaleO_5

SubscaleO_4 ~~ SubscaleO_5’

Path analysis.pdf

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