Al,
You didn't show your original command, so I'm guessing a little on the first one.
1) Typical warning when you start from text files since there is no information about how many points to expect. Not generally a problem.
2) LAS 1.2 files can only hold 4 billion points. Your tiles are of a size that your data doesn't fit in that. Note this conflicts with my guess on #1 as it suggests you started with LAS 1.2 files. Maybe you specified them for output? Or it defaults to them?
3) Your x values are such that scaling them to integers using a factor of 0.001 exceeds the +/-2 billion limit on a 32-bit integer. Also a little silly to store millimeter precision for a laser spot that is at least a centimeter in size. Did you specify this scaling? If LAStools has a default for this, it's likely 0.01.