Immunology Ebook
Hedgeworth Hennigan
Following the trajectory of scientific progress is integral to our ability to appreciate our current understanding of immunology and our ability to continue to ask important questions that uncover the complexity of the immune system and human health. As part of our PhD curriculum, students give a short overview highlighting the growth and study of various topics in immunology that we have provided here as an eBook.
Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more.
Martin Flajnik graduated from the Pennsylvania State University in 1978 with a BS in Biology. He earned an MS in 1979 and a PhD in 1983 from the University of Rochester (NY) in Microbiology and Immunology. He was a postdoc (and completed his PhD) from 1983-1988 at the Basel Institute for Immunology under Louis Du Pasquier, and rose to professor in his first independent academic position at the University of Miami (FL) (1988-97). He has been a professor at the University of Maryland Baltimore School of Medicine since 1998.
My work is centered on the evolution of the adaptive immune system, with the major goal being to understand the origins of adaptive immunity. I was involved in the early biochemical and molecular characterization of lower vertebrate MHC, and have identified several immunoglobulin and T cell receptor isotypes in ectothermic vertebrates. Our lab recently has become interested in the evolution of lymphoid tissues.
We are pleased to present you with this eBook on immunology, produced by BioTechniques in association with 10x Genomics and Bethyl Laboratories. This eBook aims to provide you with the latest on trends and perspectives within the immunology field.
What are the structures and functions of T and B cells? How do we develop adaptive immunity? What exactly is next-generation sequencing (NGS), and why would you want to sequence the immune repertoire?
Learn answers to all of these introductory concepts in immunology with our new eBook. Use this eBook as a learning resource for self-study or in classes. Test your knowledge with active learning activities and quizzes. We highlight key concepts to get you comfortable with the foundations of immunology and NGS. Comprehend and apply this insight to quantitative and deep immune repertoire analysis in your own research.
The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs.
A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.
A new eBook has been added to the MSK Library collection, Clinical Immuno-Oncology. This eBook offers focused, practical, and up-to-date content on immunotherapies used to treat a wide variety of cancer types. It covers the basic cellular and molecular mechanisms involved in cancer initiation and progression, and reviews the development of tumor specific antigens and the challenges of developing cancer immunotherapies. This resource explains the basics of cancer immunotherapy, discusses best practices, and provides recommendations from experienced clinicians in the field.
The Library has recently added a new eBook entitled Systems Immunology: An Introduction to Modeling Methods for Scientists. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes.
Immunopathology deals with physical, chemical, and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. It studies how the human defense system protects from disease and, in some cases, causes it, including autoimmune disorders and their risk factors.
AZoLifeSciences and News-Medical have compiled a collection of the most popular immunodiagnostics data articles, news, interviews, and industry insights over the last 12 months - Everything you need to know about the technological advancements of immunology.
While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.
This fun activity book includes immunology-themed crossword puzzles, word finds, mazes, and coloring pages. Take time out from your hectic research schedule to sit back, relax, and put your immunology puzzle-solving skills to work.
From natural killer cells and macrophages to dendritic cells and T cells, Bio-Techne offers cell selection and differentiation kits, cell culture media, fetal bovine serum, and an unparalleled selection of recombinant proteins and antibodies. Additionally, we continue to expand our selection of innovative tools for ex vivo cell manufacturing, making it easier for scientists to transition their research from discovery to the clinic. Learn more in this guide that describes the tools that we offer for isolating and culturing different immune cell types.
Cell surface and intracellular markers are frequently utilized to identify different immune cell types. Explore our new Cell Markers Interactive Resource Tool to find the human and mouse markers that are most commonly used in the scientific literature to distinguish different immune cell types or cell-type-specific subsets.
Flow cytometry is a powerful technique that is widely used to identify and characterize different immune cell types in heterogeneous samples. For a clear, easy-to-follow guide to designing flow cytometry experiments and data analysis, explore our Flow Cytometry Handbook.
Immune checkpoint proteins play a central role in regulating the activities of different immune cell types and represent some of the most promising targets for cancer immunotherapy. This eBook highlights some of the immune checkpoint molecules that are being investigated as immuno-oncology targets, and the products that we offer for studying these molecules.
Immune checkpoint molecules deliver signals that control the activities of different immune cell types and represent some of the most highly investigated targets for immuno-oncology research. Use our new wall poster to explore the current and emerging immune checkpoint molecules being investigated as potential cancer immunotherapy targets.
The tumor microenvironment (TME) plays a central role in inhibiting anti-tumor immune responses. Use our new poster to learn about the key mechanisms by which tumor cells, tumor-derived exosomes, regulatory T cells, myeloid-derived suppressor cells (MDSCs), and tumor-associated macrophages (TAMs) mediate immunosuppression in the TME.
RNAscope is an advanced in situ hybridization assay that allows for the visualization of single cell gene expression, targeting mRNA sequences directly in tissues. Learn more in this scientific poster showing how the technique can be utilized to evaluate the expression profiles of immune checkpoint and immune functional markers in the tumor microenvironment and the insight that this data may provide into potential combination therapies targeting different checkpoint pathways.
This new eBook provides an overview of several biological and manufacturing challenges facing the development and production of T cell therapies. It follows with examples of how Bio-Techne products and services can address these challenges at each stage of the process.
We recognize that patients and caregivers looking into cancer immunotherapy
as a potential treatment option often face an uphill battle in understanding
the technical language of immunology. To help explain the science behind immunotherapy, we have prepared this free, downloadable guide:
Cancer and the Immune System: The Vital Connection (12MB PDF).
This ebook will equip you with a basic understanding of cancer biology, how our immune system works, and the range of rapidly developing treatments that fall into the category of immunotherapies as well as definitions for the terminology of immuno-oncology.
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Unlike journal articles, which tend to focus on a very specific topic, a book provides comprehensive coverage of a topic, placing the topic within its broader context within the discipline as well as providing detailed information on the topic itself. For example, a book on a biochemistry-related topic, such as immunology, would break down its subject into chapters or sections on specific subtopics. In the case of immunology these subtopics might include such things as pathogenesis, allergies, autoimmunity, vaccines, aging and more, depending on the overall focus of the book. A book will also identify significant concepts in the field and the terminology used by professionals. That kind of breadth and depth is impossible in a short article. This makes books a good starting place for most research projects. Scholarly books also provide extensive bibliographies that can help you identify relevant materials that you may want to look at for your own research.
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