Hello Francesco,
Kisslicer will slice in a better way your model and with it, you will be able to use other material than 3ds cartridge. For example you can print HIPS for support and disolve it, the only limitation is the filament diameter, it has to be really close to 1.7 - 1.8 (max) mm diameter.
KS is not difficult to setup with cubeitmod. You just have to print some tests cube or cylinder to get a good setup per material, if your extremist you can do it by material colors.
Quickly :
After installing cubeitmod
1 - open a small cube or cylinder (like 20*20*20 mm) (it like the second cause i can watch the PS for M227/228)
2 - measure your filament diameter in several points and put the average in the material tab (name it by material/layer thickness, ex: PLA-Cubex-0.1mm)
3 - Still in the material tab, start with a flow tweak to 1, For the M227/M228 (seam effect) look on the forum or start with Giovanni values.
4 - Setup the basical function for the calibration in the style tab (1loop, 0 skin thickness, 0 jitter, extrusion&infill width to 0.5 and your layer height, infill to hollow, wipe off)
5 - Slice/Save and print your test
6 - Print finish : measure the only loop print, if its less than 0.5 mm increase the flow tweak by 0.02 per 0.1 mm if it's more i think you understand... Re-print with the new value and check if your thickness is right.
8 - After this try some print to check the surface aspect. 100 % on the solid box is a good value if your printer is not offset.
Hope it's help !