Oral GLP-1 drugs work as well as injection

[kan...@aol.com]

https://www.the-independent.com/news/health/wegovy-pill-weight-loss-drugs-b2829386.html

Well, this changes the landscape. Pills will eventually get lower in price. There will be competition. There are already two available medications. Others will follow. 

There's a medical shorthand when something is so good that whole bunches of people will benefit; they should put it in the water. Prozac and Xanax come to mind. s 

This about qualifies. Whole bunches of people will benefit. 

Dave, consider buying stock soon. Meds like this generate BILLIONS in profit. And GLP-1 meds have already proven their effectiveness and safety. Wegovy (same as Ozempic for those playing along) is already in oral form. The maker of Mounjaro may have to modify its med for oral use; but they'll get there. Even very large pharmaceuticals will see a bump in their bottom line. Think statin drugs, only on steroids (so to speak). 

Medically, obesity is a major health problem in the US. Helping people solve this issue will help a LOT. Maybe RFK can use his MAHA hat to make these meds available at a reasonable cost. Not holding my breath. Maybe the market will get prices to a reasonable level, AFTER the Pharms have profited largely. 

[David Fairchild]

Ken,  yes a potential investment opportunity to be sure. 

Better living through chemistry. Or is it?

Modern medicine it truly a marvelous thing. I think it is wonderful time to live now with median life expectancy approaching 80 vs more like 40 just 200 years ago. Gone are the days when most people could expect to die from communicable or other infectious disease, and that is a good thing. And, of course, far fewer (as a percent of population) die from accidents now. 

However GLP-1s are another in our long line of mechanisms to mitigate poor behaviors and environmental & sociological concerns rather than to correct them. With nearly 40% of American adults on statins and nearly 15% of antidepressants, I am sure it won't be long before somewhere near half of us are on GLP-1s. 

Sadly, our food supply is full of things that are bad for our long term health, and our consumption oriented society demands us to find high stress vocations that lead to mental struggles for many. 

I just wish we could change society in a way that things like statins, and antidepressant, and GLP-1 could become secondary or tertiary treatments for most rather than the go-to prescription, it seems, in most cases.

[Brian Kegerreis]

Hey

Call it poor behaviors if you will but I have a delayed full signal to the brain. If I eat a normal portion of food I feel hungry, often hungrier than I was before I started eating. I can easily eat a 2 pound sirloin and not even feel full. On several occasions I have defeated eating challenges like 72 ounce steak baked potato salad roll and eat it all under an hour. 

Ozempic has tempered my appetite. Sometimes I feel full after only eating half a regular meal. It may be easy for you to control your eating but it has never been easy for me until now. It's far easier with this medication. 

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[kan...@aol.com]

Well, it's another day; I'm going to try to not get deleted.........again

DF and BK make good points It shows that two things can be true at the same time

So, Dave, in an ideal world, things would work as you say. But barriers abound. Good food is expensive. It's out of reach for a LOT of people to eat a nutritious diet  that has adequate calories. So a lot of people eat high calorie food that is nutrition poor. Hence obesity and a lot of other problems. 

OTOH, humans evolved in a time of food insecurity. So we've become hard-wired to eat whenever we can. When our ancestors killed a Mammoth, their clan ate the whole thing. Wolves eat like this- they can consume 20+ pounds of meat in one sitting- and for the same reasons. 

So here we are, hard wired to eat whenever. And food is widely available, and widely hawked. So we (collectively) eat too much, some more than others. 

Fixing this problem is probably near impossible. Too much invested money in selling food that isn't so good for us. Our protein sources, beef,  pork, chicken, fish, etc, are not what our ancestors hunted. Too much corn syrup. Etc, etc. 

If RFK wants ANY credibility from me, he'll have to speak out loudly about this. MAHA is a joke without addressing this issue. 

On the good side, taking GLP's will lower the need for statins and blood pressure meds. It will lower cancer rates, rates of heart disease, stroke, etc. 

I was 70+ pounds overweight until I did a gastric sleeve. It was only temporarily successful. So now I take Mounjaro, Ozempic's younger brother. Works well; but I still like to eat less than smartly. 

[kan...@aol.com]

Yeah, I wasn't deleted. 

I used to be able to eat a 16 pz steak with fixings, no problem. Maybe not as much as BK; but way too much to be healthy. 

I guess we have too much Neanderthal DNA. Now where's that Mammoth; I'm hungry. 

Oh yeah; now they want to resurrect the Mammoth. Can't wait.