Our school (SPA, St. Paul, MN) currently has Prusa MK3ses and we use Cura slicer.
I have been using a Bambu X1C with AMS at home since January of this year. The print quality is fantastic- significantly better than the Prusas, allowing smaller tolerances. I have not had to do any bed leveling or tuning at all - zero. The speed is also fantastic - apparently 3x faster than the Prusas. The first layer lidar inspection & AI spaghetti detection have caught every issue but one.
The AMS is also great - it's able to switch between 4 spools of filament. It just works & I've had no issues. We had previously tried the Prusa MMUs, but we took them off because they were so unreliable. Bambu says you can't use cardboard spools in the AMS, but I've been using them without issue. Bambu has re-useable spools for filament, which is nice for reducing material use. Their filament also comes with RFIDs so the AMS automatically knows what filament it is using and adjusts the settings in the slicer automatically.
The color touch screen looks nice and works fine, but not as good as a phone.
The only maintenance I've had to do is add lube to the z-screws and adjust the belts, once each. The machine told me when to do this and had links to tutorials on screen - it was very easy.
I'm a big fan of Cura for presenting a very simple interface and hiding the complicated bits from new users. Unfortunately, right now it's only possible to use the Bambu slicer with the Bambu printers. However, Bambu has video monitoring of prints which is nice.
Pros: Fast, great quality prints, AMS works really well, almost no maintenance, no calibration, no runaway catastrophic failure prints
Cons: must use Bambu Studio slicer, touch screen doesn't always notice button presses right away (or my fingers are too big).
I'm requesting Bambu X1Cs for our next printer purchase.
chris