I see. So as I said, jsPlumb doesn't have layout functionality. If googling doesn't help you then you may have to write your own. But orthogonal layout is one of the trickiest. You might want to just try for a force directed layout first and see if you have any luck.
btw I saw your other question, about the drop down overlay. I was about to answer it and got a little busy. I'll update it shortly.