Scores

[samirah rokib]

Hi,

I just wanted to know what the scores on the table represent and what would be considered a good score. 

Thank you

[Oriol Fornés]

Hi Samirah,

Relative scores are obtained by normalizing the Scores (e.g. 11.3291 or 9.8874) between 0 and 1, wherein 0 and 1 are the minimum and maximum Scores, respectively, that can be reached for a given sequence. 

By default, JASPAR uses a Relative score threshold equal to 0.8. This is, a sequence whose Score is 80% or higher than the maximum score is considered as good. 

Alternatively, UniBind (https://unibind.uio.no/) has developed a self-adaptive threshold which is typically around ~85%. 

--

Oriol Fornés Crespo, PhD
Deputy Group Leader / Wasserman Lab
or...@cmmt.ubc.ca

Centre for Molecular Medicine and Therapeutics (CMMT)
Dpt. of Medical Genetics / University of British Columbia
BC Children's Hospital Research Institute
950 W 28th Ave, Room 3109, Vancouver, BC V5Z 4H4, Canada

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