Motif discovery in mutated/synthetic sequencs

[Yoav Ben-Simon]

I am interested in finding out how point mutations in enhancer sequences will affect the binding properties at the site of mutation, and also to see which known vertebrate TFBSs are present in synthetic enhancer sequences. Is there any tool which will allow me to map TFBSs in individual DNA sequences, which do not have any genomic coordinates associated with them?

[Anthony Mathelier]

Dear Yoav.

You can use the TFBStools R bioconductor package.

Best

AM