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Hello!
Welcome to the
JASPAR
Q&A forum.
The latest version of JASPAR is available at
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ttps://
jaspar.elixir.no
.
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Team JASPAR
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Paula Mayo
, …
Xabier de Martin
3
12/26/25
Download matrix clustering
Hi Anthony. I have successfully downloaded the motif clustering data for vertebrates ("
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Download matrix clustering
Hi Anthony. I have successfully downloaded the motif clustering data for vertebrates ("
12/26/25
Maggie Ma
,
Anthony Mathelier
2
12/19/25
Clarification on compiled data type in JASPAR
Dear Maggie. Thanks for your question and your interest in JASPAR. The matrices generated from
unread,
Clarification on compiled data type in JASPAR
Dear Maggie. Thanks for your question and your interest in JASPAR. The matrices generated from
12/19/25
Songlin Liu
, …
Ziang Liu
5
12/9/25
Bug Report: HTTP 500 Internal Server Error on JASPAR website
Confirmed! The issue has been fixed on my end. Thank you for the prompt resolution and your continued
unread,
Bug Report: HTTP 500 Internal Server Error on JASPAR website
Confirmed! The issue has been fixed on my end. Thank you for the prompt resolution and your continued
12/9/25
J.L. Xu
,
Anthony Mathelier
2
12/8/25
questions about coordinates of TFBSs from downloads
Hi. The coordinates you provide span 8 bp as they are provide in a BED file and follow the BED format
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questions about coordinates of TFBSs from downloads
Hi. The coordinates you provide span 8 bp as they are provide in a BED file and follow the BED format
12/8/25
Ed Zandro Taroc
,
Anthony Mathelier
2
12/8/25
Gallus gallus Genome TFBS data
Thanks for the note. We do not have gallus gallus predictions anymore, unfortunately. But we note
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Gallus gallus Genome TFBS data
Thanks for the note. We do not have gallus gallus predictions anymore, unfortunately. But we note
12/8/25
Moses Hei
,
Anthony Mathelier
2
12/8/25
matrix Align
Hi Moses. Could you share the exact input you provided to the tool so we can reproduce the error? On
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matrix Align
Hi Moses. Could you share the exact input you provided to the tool so we can reproduce the error? On
12/8/25
Cihan
,
Anthony Mathelier
2
12/8/25
Fast way to scan for ALL matrix profiles of a species
Hi Cihan. We recommend to use the pyJASPAR python module (https://pyjaspar.readthedocs.io/en/latest/)
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Fast way to scan for ALL matrix profiles of a species
Hi Cihan. We recommend to use the pyJASPAR python module (https://pyjaspar.readthedocs.io/en/latest/)
12/8/25
T B
,
Anthony Mathelier
2
12/8/25
Help with JASPAR enrichment - I'm probably missing something to add to the enichment
Hi. Do you ensure that the universe contain regions that overlap with all regions in your foreground
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Help with JASPAR enrichment - I'm probably missing something to add to the enichment
Hi. Do you ensure that the universe contain regions that overlap with all regions in your foreground
12/8/25
JP
, …
Anthony Mathelier
4
12/8/25
Schematic of gene region annotated with predicted TF binding sites
Hi. The TF information should be provided, isn't it in an other column? On Tuesday, June 17, 2025
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Schematic of gene region annotated with predicted TF binding sites
Hi. The TF information should be provided, isn't it in an other column? On Tuesday, June 17, 2025
12/8/25
Menglin Li
,
Anthony Mathelier
3
12/8/25
TFBS extraction tool vs. web scanning function
Hi Menglin. If you have a BED file, you can use our TFBS extraction tool https://jaspar.elixir.no/
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TFBS extraction tool vs. web scanning function
Hi Menglin. If you have a BED file, you can use our TFBS extraction tool https://jaspar.elixir.no/
12/8/25
samirah rokib
, …
Anthony Mathelier
4
12/8/25
Scores
Thanks for your message, Menglin. I hope my other message answered your question.
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Scores
Thanks for your message, Menglin. I hope my other message answered your question.
12/8/25
Melanie Fattohi
, …
Anthony Mathelier
4
12/8/25
scan for motifs in TFBS
Hi. As described on the JASPAR website (https://jaspar.elixir.no/genome-tracks/), the genome tracks
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scan for motifs in TFBS
Hi. As described on the JASPAR website (https://jaspar.elixir.no/genome-tracks/), the genome tracks
12/8/25
Irene Vides Urrestarazu
,
Anthony Mathelier
3
12/8/25
How do I interpret the score number of the predictions after scanning a TF vs a promoter sequence?
Hi Irene. The score number corresponds to the relative score of the PWM hit, which is obtained as (
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How do I interpret the score number of the predictions after scanning a TF vs a promoter sequence?
Hi Irene. The score number corresponds to the relative score of the PWM hit, which is obtained as (
12/8/25
David N Levy
,
Anthony Mathelier
2
9/19/25
Human Stat5
Hello. JASPAR provides a single TF binding profile per TF per taxon. As the human and mouse Stat5 are
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Human Stat5
Hello. JASPAR provides a single TF binding profile per TF per taxon. As the human and mouse Stat5 are
9/19/25
Johnny Chen
,
Anthony Mathelier
2
9/19/25
Scanning TFs on promoter
Thanks for your message. You must select at least one TF binding profile to run the scan on a FASTA
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Scanning TFs on promoter
Thanks for your message. You must select at least one TF binding profile to run the scan on a FASTA
9/19/25
Xuefen Xu
,
Anthony Mathelier
2
9/19/25
Duplicate Entry Found in JASPAR CORE PFMs: MA2255.1 (Max) and MA2215.1 (dm)
Thanks for raising this. These profiles directly come from CISBP, which got them from FlyFactorSurvey
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Duplicate Entry Found in JASPAR CORE PFMs: MA2255.1 (Max) and MA2215.1 (dm)
Thanks for raising this. These profiles directly come from CISBP, which got them from FlyFactorSurvey
9/19/25
Echo Evans
,
Anthony Mathelier
2
9/19/25
FASTA sequences are different from PFM
Thanks for raising this issue. The FASTA file for MA0020 is indeed incorrect and should be removed as
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FASTA sequences are different from PFM
Thanks for raising this issue. The FASTA file for MA0020 is indeed incorrect and should be removed as
9/19/25
SeongJun Kim
,
Aziz Khan
2
9/5/25
Discrepancy between JASPAR2024 website and pyjaspar results, possible species annotation issue for RUNX1
Hi Seongjun, Thanks for bringing this up. This is because the websearch first filters the profiles
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Discrepancy between JASPAR2024 website and pyjaspar results, possible species annotation issue for RUNX1
Hi Seongjun, Thanks for bringing this up. This is because the websearch first filters the profiles
9/5/25
jackhao lin
,
Anthony Mathelier
2
6/30/25
Regarding the Update and Changes of Gene Information for the Lyl1 Gene in the JASPAR Database
Dear Jackhao Lin. Thanks for reaching out. The 2022 release of JASPAR indeed contained a profile for
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Regarding the Update and Changes of Gene Information for the Lyl1 Gene in the JASPAR Database
Dear Jackhao Lin. Thanks for reaching out. The 2022 release of JASPAR indeed contained a profile for
6/30/25
Tadashi Abe
, …
Aziz Khan
5
5/28/25
Request for Permission to Use JASPAR Motif Scan and Logo Images in a Manuscript
Dear Aziz, Thank you very much for your kind response. I will include the material in my manuscript.
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Request for Permission to Use JASPAR Motif Scan and Logo Images in a Manuscript
Dear Aziz, Thank you very much for your kind response. I will include the material in my manuscript.
5/28/25
Ambuj Kumar
,
Anthony Mathelier
5
5/18/25
Clarification on JASPAR IDs MA0668.3 vs MA1993.2 for Neurod2
The base ID is associated with a specific motif for a TF. JASPAR provides binding profiles per taxon,
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Clarification on JASPAR IDs MA0668.3 vs MA1993.2 for Neurod2
The base ID is associated with a specific motif for a TF. JASPAR provides binding profiles per taxon,
5/18/25
Timothy Bailey
,
Anthony Mathelier
2
5/9/25
Could you create "jaspar2024.genreg.net" links for JASPAR 2024 matrices?
Hi Tim. Thanks for your message, support, and query. That is a very good suggestion indeed. We will
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Could you create "jaspar2024.genreg.net" links for JASPAR 2024 matrices?
Hi Tim. Thanks for your message, support, and query. That is a very good suggestion indeed. We will
5/9/25
Sager Gosai
,
Anthony Mathelier
2
5/9/25
Triggered Captcha
The captcha is expected here since it is associated with a form for users to provide us support for
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Triggered Captcha
The captcha is expected here since it is associated with a form for users to provide us support for
5/9/25
Promit Ganguly
,
Anthony Mathelier
2
5/9/25
Query regarding the JASPAR enrichment analysis
The Y-axis should be labeled -log10(pvalue). Thanks for raising the issue. On Monday, November 18,
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Query regarding the JASPAR enrichment analysis
The Y-axis should be labeled -log10(pvalue). Thanks for raising the issue. On Monday, November 18,
5/9/25
Romain Giraud
,
Anthony Mathelier
2
5/9/25
Different species for different versions of TFBS
Hi Romain. JASPAR is species agnostic within the same taxon. If you are interesting in mouse TFBSs,
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Different species for different versions of TFBS
Hi Romain. JASPAR is species agnostic within the same taxon. If you are interesting in mouse TFBSs,
5/9/25
yx zhu
,
Anthony Mathelier
2
5/9/25
backgroud model
Hi. We do not provide any background but the raw PFMs. You can transform the PFMs into PWMs with the
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backgroud model
Hi. We do not provide any background but the raw PFMs. You can transform the PFMs into PWMs with the
5/9/25
Cen T
,
Ieva Rauluseviciute
2
5/2/25
PAX3:FKHR fusion motif
Dear Cen, In order to include this motif, we need TF-DNA interaction data, such as ChIP-seq or HT-
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PAX3:FKHR fusion motif
Dear Cen, In order to include this motif, we need TF-DNA interaction data, such as ChIP-seq or HT-
5/2/25
Radka Symonova
4/15/25
search for collaboration on TFs of juvenile fish brains
Dear JASPAR community, since i am totally new in the research of TFs, I would like to find help or
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search for collaboration on TFs of juvenile fish brains
Dear JASPAR community, since i am totally new in the research of TFs, I would like to find help or
4/15/25
Anthony Mathelier
1/16/25
JASPAR survey
Dear colleagues and JASPAR users, We are conducting a survey to further improve JASPAR by
unread,
JASPAR survey
Dear colleagues and JASPAR users, We are conducting a survey to further improve JASPAR by
1/16/25
王晓
, …
Anthony Mathelier
4
11/1/24
The JASPAR database data is incomplete
Thanks for the inquiry. As I previously wrote, we are not convinced that MECP2 is a DNA-binding-
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The JASPAR database data is incomplete
Thanks for the inquiry. As I previously wrote, we are not convinced that MECP2 is a DNA-binding-
11/1/24