Blast From The Past Free Full Movie

[Sabel Kantah]

In1962, eccentric American scientist Dr. Calvin Webber believes nuclear war with the Soviet Union is imminent, and builds a secret fallout shelter beneath his backyard. Alarmed by the Cuban Missile Crisis, Calvin takes his pregnant wife Helen into the shelter. When an unexpected mechanical failure aboard an F-86 Sabre causes the aircraft to crash into the house above, Calvin assumes the worst and activates the shelter's time-locks for 35 years. With the house completely destroyed by the crash, the Webbers' neighbors and authorities assume they were killed and their property is left abandoned.

Helen gives birth to Adam who is educated to a high standard by his father (including becoming fluent in several languages) and grows up on 1950s-era pop culture like I Love Lucy and The Honeymooners, and pop standards by Perry Como and Dean Martin. Above ground, a diner opens in 1965 where a young resident named Melker gets his first job working as a soda jerk. The diner is sold and turned into a pizzeria, then becomes a punk club named Purgatory as the suburban neighborhood deteriorates over the decades into an inner city ghetto. By 1995, Melker is a bitter middle-aged alcoholic living in the club's condemned remains.

When the shelter unlocks in 1997, Calvin mistakes the now-blighted neighborhood for a post-apocalyptic wasteland of irradiated mutants and decides the family must stay underground over the objections of Helen, who, unlike Calvin (who enjoys the seclusion) and Adam (who knows nothing else), has never taken to living in the shelter. With supplies running out and Calvin falling ill, Adam leaves the shelter for the first time to obtain food. He meets Melker, who had encountered Calvin the previous night, bursting through the floor in his radiation suit. The old man convinces himself that Adam is a god. Marveling at the outside world, Adam purchases supplies, but then cannot remember his way back to the elevator.

Trying to sell his father's classic baseball cards at a hobby shop, Adam meets Eve Rustikov, who stops the store owner from cheating Adam and is fired. Eve drives Adam to a Holiday Inn in exchange for a rare card but returns the next morning out of guilt. Adam asks her to help him. Unaware of the value of money, Adam agrees to her request for $1,000 a week, while also asking Eve to help him find a wife who is "not a mutant" and is from Pasadena, California, per his mother's advice. Adam meets Eve's gay housemate and best friend Troy, who provides him with advice and a fashion makeover.

Eve and Troy take Adam to a '40s swing-style nightclub to find him a wife. Adam attracts the attention of several women, including Eve's nemesis Sophie. Jealous, Eve reconnects with her ex-boyfriend Cliff and gets him to provoke Adam into a fight, relenting when Adam demonstrates his boxing skills (having trained every day with his father). Eve is disgusted and goes home. Troy later tells her Adam left the club with Sophie. Adam returns, explaining that he politely rejected Sophie's advances, as he could only think about Eve. He and Eve kiss, but when Adam admits the truth about his past and his desire to take her to be his wife "underground", she asks him to leave.

Finding the club, where Melker has recruited a full congregation to worship him, Adam returns to Eve's house, where she is waiting with psychiatrist Dr. Nina Aron and her assistant to have him committed. Initially cooperating, Adam escapes, though not before asking Eve and Troy to collect his things and pay his hotel bill. In his hotel room, Troy and Eve find toiletries and clothing from the '60s and absurdly valuable stock certificates in companies like IBM (which Calvin had previously written off as "worthless") and deduce that Adam is not crazy and was telling the truth the whole time.

As Melker and his cult load supplies into the shelter, Calvin prepares to seal his family inside again. Eve spots Adam outside the club. They embrace and Adam takes her to meet his parents. Impressed with Eve, Calvin and Helen agree to set the shelter's locks for two months while Adam and Eve make arrangements. During this time, Adam and Eve sell the stocks to build his parents a new home in the country, identical to their house that was destroyed, and purchase and restore a red 1960 Cadillac convertible. They help Melker rebuild the pub into a '50s-themed nightclub after convincing him that Adam is not God.

Adam reveals to his father there was never an atomic war and that the Soviet Union collapsed peacefully, ending the Cold War. Unconvinced, Calvin plans to build a new fallout shelter as Eve watches while playing with her engagement ring.

The film received mixed reviews from critics. On review aggregator website Rotten Tomatoes, 58% of 81 critics gave the film a positive review, with an average rating of 6.1/10. The website's critics consensus reads, "Cute idea, but not consistently funny".[1] On Metacritic, the film holds a score of 48 out of 100 based on 19 critics, indicating "mixed or average reviews".[2] Roger Ebert gave the film three out of four stars saying "the movie is funny and entertaining in all the usual ways, yes, but I was grateful that it tried for more: that it was actually about something, that it had an original premise, that it used satire and irony and had sly undercurrents."[3]

The eruption of Tambora was ten times more powerful than that of Krakatau, which is 900 miles away. But Krakatau is more widely known, partly because it erupted in 1883, after the invention of the telegraph, which spread the news quickly. Word of Tambora traveled no faster than a sailing ship, limiting its notoriety. In my 40 years of geological work I had never heard of Tambora until a couple of years ago when I started researching a book on enormous natural disasters.

We camped a third of the way up the mountain, and set out at dawn for the summit, wending around boulders the size of small cars that were tossed like pebbles from the erupting volcano nearly two centuries ago. Our guide, Rahim, chose a trail that switched back and forth for about four miles. The day was warm and humid, the temperature in the 70s. Grasses in places were charred black, burned by hunters in pursuit of deer.

I was excited to approach the site of one of the most important geological events since human beings first walked the planet. Yet as I looked up at the mountain, I realized I had another purpose in mind. The climb was a chance to reassure myself that after treatment for two kinds of cancer in the past decade, I could still master such a challenge. For me, then, it was a test. For the two porters, striding along in flip-flops, it was a pleasant stroll in the country.

Failing crops and rising prices in 1815 and 1816 threatened American farmers. Odd as it may seem, the settling of the American heartland was apparently shaped by the eruption of a volcano 10,000 miles away. Thousands left New England for what they hoped would be a more hospitable climate west of the Ohio River. Partly as a result of such migration, Indiana became a state in 1816 and Illinois in 1818.

Three thousand feet deep and more than three miles across, the crater was as barren as it was vast, with not a single blade of grass in its bowl. Enormous piles of rubble, or scree, lay at the base of the steep crater walls. The floor was brown, flat and dry, with no trace of the lake that is said to collect there sometimes. Occasional whiffs of sulfurous gases warned us that Tambora is still active.

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Will protein structure search tools like AlphaFold replace protein sequence search with BLAST? We discuss the promises, using structure search for remote homology detection, and why protein BLAST, as the leading sequence search tool, should strive to incorporate structural information

BLAST1 is widely used in molecular biology to search for nucleotide and protein sequences. Three decades after BLAST was introduced, there were major breakthroughs in structure prediction, and tools such as RoseTTAFold2 and AlphaFold3 emerged. Consequently, every protein sequence in the major sequence databases now comes with a model of how it folds in 3D. While this does not affect (non-coding) nucleotide sequences, it begs the question of whether a search over 3D protein structures will replace a search over protein sequences. Is Protein BLAST a thing of the past?

While BLAST searches are a powerful tool in function prediction, they are limited. Sequences can degrade significantly and still fold into similar 3D structures that perform the same or similar functions.

These examples suggest that AlphaFold may be able to step in where BLAST cannot find significant similarity. Hence, the question arises: How can this be achieved systematically? To this end, there are tools such as Foldseek9, DALI10, and 3D-AF-Surfer11, which scan and compare structures using autoencoders, distance matrix alignment, and dedicated fingerprints, respectively. While these tools exist, they still need to be more widespread and straightforward enough to compete with BLAST searches over sequence databases. A synergy is needed that integrates them into a classic BLAST sequence search. A first step in this direction has been recently taken by a study comparing reciprocal best BLAST hits and reciprocal best structural hits12 and by nearest neighbour search on machine learning embeddings of sequences13.

As encouraging as the 95% AUC for structure comparison may be, the availability of high-quality structures may be a limitation. It is estimated that 30% of all eukaryotic proteins contain disordered regions of 50 or more consecutive amino acids15, which can be expected to be of poor quality in 3D structure prediction. These regions would be amenable to sequence search with BLAST, while they would not be suitable for a direct structural search. To assess how such a large percentage extends to the whole of the AlphaFold database, we computed the average confidence score for all AlphaFold structures. We found that 80% of all AlphaFold structures have a pLDDT confidence score of 70% or better, meaning that they are modelled well with generally good backbone prediction (see Supplementary Note 4). This means that there is substantial structural data available which is of suitable quality.

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