difference between .nii and nii.gz

[Maus E]

Hi all,
I would like to save my segmentation as .nii however ITK automatically suggests saving it as .nii.gz. As I understand both are nifti files so can I just force it to save as .nii?
I tried to do so but i feel like something went with the orientation and partial segmentations when I use it in the next program for analysis. However since I can't use .nii.gz, I don't if this problem is caused by just deleting .gz when saving or because of a different issue.
Can some one help me?
Thanks in advance
Maurits

[Philip A Cook]

You can save as .nii from SNAP and it should write the uncompressed nii file.

One thing that can cause trouble is having both

segmentation.nii
segmentation.nii.gz

in the same directory.

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