hi Michael,
from the file path, it looks like you are running on Windows. in this case, I suspect that the reason tetgen failed was because you are trying to mesh a very large volume, and requires memory more than 4GB. the tetgen coming with iso2mesh-1.9.6 is a 32bit exe and does not support large memory. You will have to update your iso2mesh to the latest github version to call the tetgen_x86-64.exe.
also, to be sure this was the cause, you can set a break point at
      one of the below system() calls and print out the full command
      when calling tetgen, and try to run it inside a shell (cmd or
      powershell)
    
https://github.com/fangq/iso2mesh/blob/master/surf2mesh.m#L110-L114
CCing brainstorm developer Francois in case this is a known
      brainstorm issue.
    
Qianqian
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