This study is open to adults, ages 18-65, who have panic disorder. Participants in the ongoing studies will receive
free Cognitive-Behavioral Therapy (CBT), one of the most effective treatments for panic disorder. The study examines whether a medication (an FDA approved antibiotic, D-Cycloserine), will improve how well CBT works given in low dosages one hour before each therapy session. Previous, smaller studies have shown that D-Cycloserine may increase people’s ability to remember and use the strategies learned in therapy and thus may enhance the therapy process.
Participants in this treatment study are randomly assigned (like a coin toss) to receive either the medication or a placebo pill (sugar pill) in addition to CBT. In this study we will also examine genetic markers that may be associated with panic disorder. A small blood sample will be drawn from each participant to use for this testing. The information from this sample, as well as the treatment, will be kept confidential.
David F. Tolin, Ph.D., ABPP
Director, Anxiety Disorders Center and Center for Cognitive Behavioral Therapy
The Institute of Living
Adjunct Associate Professor of Psychiatry
Yale University School of Medicine
200 Retreat Avenue
Hartford, CT 06106