Yes, both machines are Windows 10 of course... the software called Synergy has the same issue, thats why I wanted to try out this software, and it is not working too.
The only remote one which does work is the one by MS called Mouse without Borders.
And no... I mean UWP apps. For examle the Task Menu, the Windows Store, the Windows 10 Settings Window. Mouse wheel scroll does not work. It works though in normal win32 apps like Explorer, Chrome, and so on.