Processing Light and Heavy chain sequences

[San Emmanuel James]

Hello,

I am new to the workflow, 

Would you point me to how I would process sequences that comprise both heavy and light chain?

For example, should I run igblast on each set separately? or combine them and run igblast together? if separately, how do then get clones detected in both heavy and light chains? 

Does the documentation is quite robust for a single chain but I am having abit of a challenge with analysis of both heavy and light chains. 

Please advise.