Conversion of data to X2K

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Charlotte Jendresen (DK)

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Apr 19, 2021, 6:58:24 AM4/19/21
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Dear iLINCS

 

I have tried working on a dataset of differentially expressed genes directly in the X2Kweb and on iLINCS signature analysis tools –> exporting data to X2Kweb, and the results are not the same.

 

Since X2Kweb only has the possibility of submitting a list of gene symbols, and iLINCS signature can be a list of gene IDs with log2(fold change) and adjusted p-values, I was wondering how you convert the data when submitting to X2Kweb analysis if I submit geneIDs with p-values and log2(FC)?

 

 

Kind regards,

Charlotte Jendresen

 

Senior scientist, Drug Discovery

 

Orphazyme A/S

Ole Maaløes Vej 3

DK-2200 Copenhagen N

Denmark

E-mail: c...@orphazyme.com

www.orphazyme.com

 

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mario.me...@gmail.com

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Jun 28, 2021, 2:53:26 PM6/28/21
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Dear Charlotte,
I apologize for belated reply. For some reason I missed your message. iLINCS interacts with X2Kweb by submitting the IDs of the currently selected genes. By default this is the top 100 most differentially expressed genes, but you can modify the list by clicking "Modify the list of selected genes" button and using the interactive volcano plot to select a different set of genes.
Best,
Mario

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