Add Macaca fascicularis T2T-MFA8v1.1 (GCF_037993035.2) to IGV Reference Genomes
Shicheng Guo
Dear IGV Support Team,
I hope you are doing well. I am writing to request the addition of a new high-quality non-human primate reference genome to the IGV genome list:
Macaca fascicularis (crab-eating macaque) T2T-MFA8v1.1, RefSeq assembly GCF_037993035.2.
This assembly, released by Shanghai Jiao Tong University and annotated by NCBI (RefSeq release date March 31, 2025), represents a telomere-to-telomere, complete genome for Macaca fascicularis. It is now one of the most accurate and complete primate references and is increasingly important for translational research, toxicology studies, and preclinical development work.
Key Assembly Details:
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Assembly: T2T-MFA8v1.1
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RefSeq Accession: GCF_037993035.2
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Genome size: ~3.1 Gb
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Chromosomes: 22 autosomes, X, Y, and MT
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Assembly level: Complete Genome
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Sequencing technologies: PacBio Sequel, ONT PromethION, Illumina NovaSeq
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Assembly method: Verkko v1.2
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Annotation: 40,596 genes (21,271 protein-coding)
NCBI Genome link:
https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_037993035.2/
Given the rapid adoption of this reference in the community—particularly within non-human primate genomics and siRNA therapeutics—having this assembly available directly within IGV would significantly streamline visualization workflows for many users.
If helpful, I would be happy to provide FASTA, GFF3, or any other required files to facilitate integration.
Thank you very much for your time and for maintaining such an essential tool for the genomics community.
Best,
Shicheng
