BAM header errror: bad magic number

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Dinesh Gandhe

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Oct 10, 2025, 8:41:26 AMOct 10
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BAM header errror: bad magic number. This could be caused by either a corrupt or missing file.Screenshot 2025-10-10 181026.png

igv-help

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Oct 10, 2025, 10:18:36 AMOct 10
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Did you have a question? 

Yiping Zhan

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Oct 21, 2025, 9:34:34 AMOct 21
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I have the same issue. When I use a much older version of IGV web app (1.7.0) things work with exactly the same session file. However, with a recent version (2.3.4) I see the error shown below. Does anyone know what is going on?

Thanks,
Yiping
Screenshot 2025-10-21 at 9.31.48 AM.png
Screenshot 2025-10-21 at 9.33.34 AM.png

Yiping Zhan

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Oct 21, 2025, 12:16:13 PMOct 21
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After drilling down fixes mentioned in this thread https://groups.google.com/g/igv-help/c/JjYQqziEhx4/m/EPaciXY3BAAJ and clearing my browser cache the error message went away.
Thanks,
Yiping

igv-help

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Oct 23, 2025, 11:28:20 AMOct 23
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Glad to hear it's working for you now. Thanks for letting us know.
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