IDR on CUT&RUN data

Emi Ling

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Mar 1, 2020, 3:56:19 PM3/1/20

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Hello,

Has IDR been tested on peak callers for CUT&RUN data? (e.g. SEACR described here and here) If so, are there any parameters you would recommend?

Thank you!

Georgi Marinov

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Mar 1, 2020, 5:11:25 PM3/1/20

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Hi,

It has not been properly calibrated for SEACR, but as long as you an define a meaningful and appropriate ranking metric plus provide a sufficiently large number of peaks, it should be possible to run it on the output.

Georgi

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Emi Ling

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Mar 17, 2020, 1:46:03 AM3/17/20

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Thank you! I will give it a try.

On Sunday, March 1, 2020 at 5:11:25 PM UTC-5, Georgi Marinov wrote:

Hi,

It has not been properly calibrated for SEACR, but as long as you an define a meaningful and appropriate ranking metric plus provide a sufficiently large number of peaks, it should be possible to run it on the output.

Georgi

On 2020-03-01 12:56, Emi Ling wrote:

Hello,

Has IDR been tested on peak callers for CUT&RUN data? (e.g. SEACR described here and here) If so, are there any parameters you would recommend?

Thank you!

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