meaning of the IDR output plots

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TRypdal

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Mar 14, 2013, 11:35:48 AM3/14/13
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Hi,

I'd be glad if anyone could provide a basic overview of what the .ps file produced by the IDR is showing.

Apologies if this was somewhere in the documentation and I've missed it.

Thanks!

Anshul Kundaje

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Mar 14, 2013, 12:10:35 PM3/14/13
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Take a look at this IDR-basics documented compiled by Qunhua. It will introduce you to all the types of plots and also provide an intuitive explanation of IDR. I will attach this document to the IDR pipeline page https://sites.google.com/site/anshulkundaje/projects/idr and the main page of the IDR discussion group https://groups.google.com/group/idr-discuss.

In the IDR plots, 

- the left most (top and bottom) correspond to 'correspondence curves using all peaks from both replicates'. See the 101 document for what the correspondence plot is.
- the middle (top and bottom) correspond to 'correspondence curves' using only matched peaks (i.e. peaks that are present in both replicates) from both replicates
- The rightmost plot is the IDR vs peak rank plot i.e. the IDR scores as you go down the ranked list of matched peaks (ranked by their inferred IDR scores)

The more technical full-blown version of this is in the statistics IDR paper http://projecteuclid.org/euclid.aoas/1318514284

Thanks,
Anshul.


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IDR101.pdf
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