Of course. On the Filters tab, the Response Type and Size box has a dropdown that allows you to hide images, or show only other content types, but it doesn't enable the particular combination you've asked for.
No worries, you can easily write a FiddlerScript Rule to do this.
In Fiddler, click Rules > Customize Rules.
Scroll to either the OnPeekAtResponseHeaders or OnBeforeResponse methods. Inside the method, add the following lines:
var sMIME: String = oSession.oResponse.MIMEType;
if (sMIME.Contains("image/") || sMIME.Contains("script")) {
oSession["ui-hide"] = "FiddlerScript: Hide scripts and images";
}
Save the script file and you will find that images and script requests are now hidden from the Web Sessions list.