1) Sorry, I assumed you already have a matrix with the travel times.
The standard "distance matrix" is often in a time unit in VRPTW because time windows and service times are also compared respectively added to the "distance". If you just had distances, I would suggest to use times instead. If you need the distance, maybe add that as a new matrix, e.g. when you have a distance constraint.
2) The customers have as time window earliest 0, due date could also be 45 minutes or even slightly less if you take into account that the vehicle needs to arrive in time at the depot before 45 minutes.