Grading, association to HER2 status stratification

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R Quintino

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Jan 10, 2020, 12:07:14 PM1/10/20
to HEROHE Grand-Challenge
Hi Eduardo, organization team & everyone!

One question, it's known (mentioned in competition page) that BC grading association with HER2. Were these cases stratified or all share the same BC grading?

Concern is, if dataset has several BC grades, and these are not properly balanced regarding her2, then grading probably is a necessary, most relevant  (and only?) association factor/signal for HER2.

But that would make this a grading competition mostly? Not necessarily related to the described outcome we want to achieve. (will the results be able to control for BC grade level?)

Also, because if stratified for grading, any grading signal won't be relevant for her2 in the dataset, and so we should focus on other morphological features/possibilities.

Don't know if anything can be shared related to this :), but leave it anyway.

thanks!
Rui

Eduardo Conde-Sousa

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Jan 13, 2020, 6:23:30 AM1/13/20
to R Quintino, HEROHE Grand-Challenge
Hi 

All grades are represented in the challenge. We do not garante that its balanced.  

best
Eduardo


******************************************************************************************
Eduardo Conde-Sousa
INEB – Instituto Nacional de Engenharia Biomédica
i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Rua Alfredo Allen, 208 | 
4200-135 Porto, Portugal
******************************************************************************************


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