I replied earlier, but I think it might have been held since I posted a link in the content. The Hardrock can get Kenwood format CAT and switch bands on its own. On the HR50 website, look under Transceiver Interfacing and see the section on the Flex-1500. It describes how to do it with PowerSDR, but the instructions should work for software that can emulate Kenwood CAT to a serial port. You will have to connect the USB port of the amp to the computer running the SDR application.
The N2ADR board will require less configuration once you have the Pico on it configured, but it will be limited to software that is writing the proper I2C parameters while the direct CAT might give you other options.
Luke - AE5AU