Hi Irodmedia,
I'm surprised your board does anything without 2.5V. That voltage is necessary for the PLLs to work in the FPGA. Can you please measure the 2.5V again on both sides of FB28 and FB30 relative to ground?
Is it correct that no software is able to connect? Software must be able to connect to read and change and IP settings, so the 192.168.10.38 seen in SparkSDR is probably just a software leftover and has nothing to do with the current HL2 settings.
Did the footswitch inject power into the HL2? Any passive switch connected to the key/ptt input should not be a problem, even if all 3 wires are shorted together. Those pins aren't even associated with the 2.5V source.
See the schematic at:
73,
Steve
kf7o