Antacids:
Neutralise gastric acid, aluminium containing antacids contribute aluminium to
the diet and may cause constipation or lead to phosphorous deficiency. Longterm
or inappropriate use can lead to Aluminium toxicity. Calcium containing
antacids contribute calcium to diet and may cause constipation . Magnesium
containing antacids contribute magnesium to diet and may cause diarrhoea.
Longterm use may lead to magnesium toxicity.
Antiboitics:
When amoxylin is given without regard to food nausea and diarrhoea are common
side effects.It is better to take medicine with food to reduce nausea.
Clarithromycin:
when taken it may cause taste alteration nausea and diarrhoea.
Metronidezol:
May cause taste alterations and no alcohol should be used during
treatment if alcohol is given and for 24 hrs afterwards alcohol can
react with metronidezole and result in nausea , vomiting, headache, cramps .
Antisecretary agents:
Inhibit gastrophasis secretion . Citnitidine may increase formation of toxic
metabollites. Nizartidine when taken with tomato based juices its potency is
reduced.
Omeprazole and
rebeprazole: They inhibit secretion of acids may
interfere with iron absorption. When iron supplements are necessary they should
be given 2 hours before or after taking protonpump inhibitors.