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The launch of EVERSE 8 saw Electro-Voice set a bold new benchmark for battery-powered portable speakers by bringing real pro-audio performance into play, and the EVERSE name quickly rose through the ranks to represent the gold standard in the segment.

EVERSE 12 sets itself apart with professional-grade specifications at an appealing price. With a maximum SPL of 126 dB, deep low-frequency response (45 Hz) and wide coverage (100 x 60), it delivers truly impressive performance. Perfect for DJs, musicians, rentals and events, it's a portable powerhouse suitable for various scenarios, offering signature clarity with serious output capability. The custom Li-ion battery provides 12+ hours at 100 dB or 6+ hours at max output. Weatherized design, a high-output titanium-diaphragm compression driver, true wireless stereo and QuickSmart Mobile app control all add up to ensure EVERSE 12 excels indoors and outdoors.

The EV QuickSmart Mobile app streamlines wireless control for EVERSE 12, allowing adjustment of audio, effects and mix functions via phone or tablet. Pairing up to six Bluetooth-equipped Electro-Voice speakers is possible, along with support for Bluetooth true wireless stereo streaming. Local configuration is swift with the single-knob encoder, and the intuitive interface simplifies shaping your sound. The integrated 12 V DC port powers wireless microphone systems, and a USB-C charging port is provided for mobile devices. Connectivity includes two XLR/TRS combo jacks, a 3.5 mm stereo jack and a TRS footswitch input.

EVERSE 12 is precision-crafted for easy transportation, while embodying Electro-Voice's reputation for durability and reliability. Featuring a soft-touch handle and lightweight construction, it easily mounts on a tripod, acts as a stage wedge, or projects upward with adjustable angles. In combination with the rugged polypropylene enclosure, utilizing the included weatherized input cover allows EVERSE 12 to achieve an IP43 rating (water-resistant for splashes and light rain) when running on battery power during Bluetooth streaming. The optional rain cover and duffel bag further enhance weather protection and convenience. Built-in feet with no-skid rubber pads ensure stability.

The QIAsymphony SP is a versatile nucleic acid purification instrument providing high-quality nucleic acids compatible with with most common downstream assay technologies, such as real-time PCR, digital PCR, and next generation sequencing (NGS). The large range of a dedicated QIAsymphony kits enables optimized purification of genomic DNA, cell-free circulating DNA, RNA, bacterial and viral nucleic acids from a wide range of starting materials. The QIAsymphony AS extends the capabilities of the QIAsymphony SP by integrating automated PCR assay setup, which, in combination with the Rotor-Gene Q and QIAGEN real-time and end-point PCR kits, enables you to optimize your PCR workflow and maximize your efficiency.

Extending the QIAsymphony SP with the QIAsymphony AS results in a fully integrated system that can automate sample preparation and assay setup workflows without manual interference. Manual pipetting steps prone to human error are eliminated, making this system ideal for laboratories that perform complex assays on a day-to-day basis. The QIAsymphony AS provides active cooling of reagents, eluates and assays, enabling safe and reproducible assay setup. The QIAsymphony AS supports setup of multiple assays per run or sample. A customization service is available for in-house assays.

The QIAsymphony SP and the QIAsymphony SP/AS instruments deliver state-of-the-art process safety and standardization features. Tip guards minimize the risk of cross-contamination and built-in UV lamps provide effective worktable decontamination. Bar code reading of samples and reagents enables full tracking throughout the entire purification and assay setup procedure. Chronological electronic documentation of results is provided, including information about sample IDs, their positions, and the lot number and expiry date of sample preparation and PCR reagents. Multi-level user management provides a record of which user was responsible for sample processing. Electronic result files may be automatically printed via a networked printer, or downloaded using a USB stick for archiving purposes. The QIAlink software which is available separately (?) can handle communication with Laboratory Information Management Systems (LIMS).

The QIAsymphony Cabinet SP/AS (see figure " QIAsymphony Cabinet SP/AS") is specifically designed for correct positioning of the QIAsymphony SP/AS instruments. The QIAsymphony Cabinet SP/AS comprises two separate parts: one for the QIAsymphony SP and one for the QIAsymphony AS. If you have both QIAsymphony SP and QIAsymphony AS instruments, you need both cabinet, which are positioned side by side. If you have only a QIAsymphony SP instrument, only the QIAsymphony Cabinet SP is required. The QIAsymphony Cabinet SP and the QIAsymphony Cabinet AS each contain a waste compartment into which used tips from the worktable can be ejected.

The QIAsymphony SP is ready-to-run and requires only minimal installation. Laboratories already operating a QIAsymphony SP can easily upgrade their system onsite with a QIAsymphony AS module. The QIAsymphony AS directly interfaces with the QIAsymphony SP. To reduce manual handling steps and minimize the risk of sample contamination, samples processed on the QIAsymphony SP can be transferred automatically to the QIAsymphony AS (integrated operation). For extra flexibility, the QIAsymphony SP and AS can also be operated independently. Samples that have been processed earlier in the day, or that have been processed on a different QIAsymphony SP, may be manually transferred to the QIAsymphony AS (see figure " QIAsymphony workflows").

Sample preparation and assay setup runs are defined using the touchscreen. Simply load drawers with the required samples, reagents, and consumables. When each drawer is closed, a detailed inventory scan is performed. This ensures that the worktable is correctly set up for the selected protocols. After sample preparation, either remove purified nucleic acids from the eluate drawer or automatically transfer eluates to the QIAsymphony AS via the transfer module for assay setup. After assay setup, assays can be transferred directly to a real-time PCR cycler for analysis.

QIAsymphony Kits are safe and exceptionally easy to use. Ready-to-run, bar code-labeled reagent cartridges are prefilled with all reagents required for the purification procedure, including accessory enzymes (see figure "

Reagent cartridges are prefilled with all reagents required for the purification procedure, including accessory enzymes, and are labeled with 2D bar codes. Partially used cartridges can be resealed for later use, giving you complete cost control.

QIAsymphony operating software guides the user step-by-step through setting up a sample preparation or assay setup run, with options to select and adapt standardized protocols. Required volumes of buffers, reagents, master mix, and controls are automatically calculated, and the user is informed of the number and type of consumables to be loaded. Transfer of sample loading information from the QIAsymphony SP to the QIAsymphony AS is convenient and reduces the number of steps required for assay definition.

The QIAsymphony SP/AS instruments provide standardized communication interfaces. Work lists and rack files may be imported to the instruments, enabling automatic run definition before samples are received in the laboratory. After assay setup, sample lists can be exported to selected real-time PCR cyclers. This bi-directional data exchange allows integration of QIAsymphony SP/AS instruments into laboratory information management systems (LIMS).

QIAGEN makes it easy to keep up to speed with the latest automation and sample processing technologies. Simply exchange an old instrument for a new one. Improve your efficiency by trading in a competitor instrument or trading up with an older QIAGEN instrument.

For most sample types, incubating longer than specified in the pretreatment protocol for the QIAsymphony DNA Investigator Kit does not increase yields. However, lysates can be incubated overnight without negatively affecting the quality of the extracted DNA.

No. The use of internal controls with the QIAsymphony Virus/Bacteria Kits is not mandatory. When using internal controls, they are added to the carrier RNA mixture (total volume of the mixture must be 120 l).

You will also require the tool to change the O-rings. Part number for this tool is: 9019164. This tool set includes one bag of 32 O-rings.

We recommend replacing O-rings on all pipetting channels, once a month.

No. All solid materials (e.g., swabs, blood card punches, chewing gum) must be removed completely from the lysate before performing automated extraction on the

QIAsymphony SP. The QIAshredder can be used to increase sample recovery from some solid materials. For more information, see the corresponding pretreatment protocol.

For purification of RNA on the QIAsymphony SP, tissue samples require mechanical disruption and homogenization in the supplied lysis buffer (Buffer RLT Plus), e.g., by using the TissueLyser or TissueRuptor. Cultured cells should be lysed by vortexing in the lysis buffer contained in the kit.

In general, magnetic particles are not carried over into QIAsymphony eluates. However, if high amounts of genomic DNA are purified (large number of white blood cells in the sample) magnetic-particle carryover may be observed. If carryover does occur, magnetic particles in eluates will not affect most downstream applications. If magnetic particles need to be removed before performing downstream applications, tubes or plates containing eluates should first be placed in a suitable magnet and the eluates transferred to a clean tube.

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