And do you mean to tell that none of those "Don't use the cantilevered design" answers did not provide any arguments? The problem is that there is lack of structural stiffness in vertical direction - the outer edge can wobble easily and that will dramatically affect your print quality, _especially_ if you want to go for 500 mm size print bead.
The best thing you can do is add two more drive screws approximately at corners of the outer edge so that all three screws create a nice large triangle and with 2 linear slides on the other two corners you will be just fine. And couple all the screws and Z axis motor with a timing belt. The overall result might look something like this (although this guy placed corner drive screws right next to linear slides, that does not matter that much, it allows for some savings in materials):
Please do _not_ copy the solution for motion in xy plane - unsupported round rails for 500 mm print size require very large diameter to avoid any flexibility in them, so use aluminium support structure and some linear rails for both horizontal axes.