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Adderall is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Adderall, a brand name, is a combination of amphetamine and dextroamphetamine, which are central nervous system stimulants. Taking Adderall may help increase the ability to focus, pay attention and control behavior.
The drug increases the activity of the brain chemicals dopamine and norepinephrine, according to the National Institute on Drug Abuse (NIDA). Adderall mainly stimulates the sympathetic nervous system, which triggers the body’s “fight or flight” responses, such as pupil dilation, increased blood pressure and heart rate and increased sweating. Amphetamine and dextroamphetamine increase the availability of norepinephrine and dopamine in the brain. Together, these brain chemicals play a vital role in wakefulness and attention.
Adderall is available as either an oral tablet under the brand name Adderall or an extended-release oral tablet under the brand name Adderall XR
The Food and Drug Administration (FDA) have approved Adderall for the treatment of ADHD and narcolepsy.
ADHD
ADHD is a condition that usually appears in childhood or early adolescence. Characteristic symptoms include hyperactivity, impulsiveness, and difficulty paying attention.
Research shows that these symptoms are partly the result of decreased dopamine activity in the brain. Dopamine is a brain chemical that plays an important role in movement, motivation, and attention.
Adderall increases the availability of dopamine in the brain, helping alleviate ADHD symptoms.
NARCOLEPSY
Narcolepsy is a chronic sleep disorder that causes the following symptoms:
- excessive daytime sleepiness
- sleep attacks, in which a person experiences sudden overwhelming sleepiness
- hallucinations
- sleep paralysis
- disrupted nighttime sleep
- cataplexy, or sudden muscle weakness that occurs in response to strong emotion
Narcolepsy may stem from the death of a particular type of brain cell. These cells produce the chemical hypocretin, which is essential for regulating the sleeping and waking cycle. Stimulant medications, such as Adderall, boost the levels of a brain chemical called norepinephrine, which helps promote wakefulness. Taking stimulants at the start of the day can promote daytime wakefulness, which may also help a person sleep better at night.
Common side effects of Adderall include headaches, dizziness, and anxiety. Common side effects of Adderall include:
- headaches
- dizziness
- anxiety
- difficulty sleeping
- decreased appetite
- stomachache
Children taking stimulant medications such as Adderall may also experience:
- temporarily delayed growth
- tics
- moodiness and irritability
In some cases, Adderall may cause more serious side effects. People should phone a doctor right away if they notice the following symptoms in themselves or a child in their care while taking Adderall:
- blurred vision
- increased blood pressure and heart rate
- chest pain
- shortness of breath
- fainting
- cognitive impairments
- hallucinations
- aggression
- delusional thinking
- racing thoughts
People who feel as though they are experiencing a medical emergency should phone 911 or the emergency number in their area.
The risk of serious side effects is higher among people with certain preexisting medical conditions, such as:
- heart problems or heart defects
- a history of stroke or heart attack
- high blood pressure
- circulatory problems
- hyperthyroidism
- seizures
- glaucoma
- depression or anxiety
- bipolar disorder
- drug misuse or addiction
- recent use of monoamine oxidase inhibitors
- an allergy or hypersensitivity to stimulant drugs
While Adderall is a safe treatment option for many people, there are several possible risks. These include or relate to:
PREGNANCY AND BREASTFEEDING
According to the FDA, there are no adequate, well-controlled studies investigating the effects of Adderall use during pregnancy.
It is possible that infants who have exposure to amphetamines during gestation are at increased risk of:
- premature birth
- low birth weight
- amphetamine withdrawal symptoms
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