Number of genes in the Hallmarks gene set

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Joy E

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Jul 2, 2025, 1:41:49 PMJul 2
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Good morning GSEA Team,

I hope this message finds you well.

I’m currently using the Hallmark gene sets in my analyses and would like to confirm the most up-to-date gene counts for accuracy. In the v2025 file I downloaded, I found a total of 7322 genes across all Hallmark sets, with 4384 unique genes. However, according to the original 2016 paper, Table 1 lists a total of 7343 genes when summing across the sets. I have been through the release notes but have not found anything that has helped.

Could you please confirm the current official total and unique gene counts for the Hallmark collection?

Kind regards,
Joy

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