Internal : End of stream errors encountered on client side, compatibility with grpc-netty-shaded - 4.1.100.Final

[Mohit Nandargi]

Hi team,
We're encountering an 'INTERNAL: Encountered end-of-stream mid-frame' error on our gRPC client.
Our setup details are:
gRPC Version: 1.60.1
Netty: grpc-netty-shaded bundling Netty 4.1.100.Final
Client Stub: blockingStub
I'm aware of the known gRPC-Java issues with Netty 4.1.111.Final that were subsequently fixed in gRPC 1.65.0+.
My core question is: Could this 'end-of-stream mid-frame' error be indicative of an underlying gRPC-Java/Netty incompatibility or bug in version 1.60.1 (even with Netty 4.1.100.Final), or is it more likely a symptom of genuine network issues like packet loss on the client side?

Any insights into the most probable causes would be greatly appreciated! Thank you!