En fait, IMHO, le DSM, meme si il a son utilite, c'est un peu un bazooka cote diagnostic
Il faut debattre de la semiologie fine du disgnostic differentiel TDAH vs Bipolaire vs Borderline
Excerpts from my 2007 correspondence with Dr Bill Dodson (Please do mention his name)
Dear Dr. Anderson,
I apologize for taking so long to get back to you but I wanted to take the time to respond to your
email in the depth it requires. The subject line of your two email contacts was so dramatic that I
tended toward caution before I responded.
Your email touches on a number of factors to which I have found it necessary to devote the better
part of a chapter in my new book. As you point out, the problems come from
1. imprecision in diagnosis. Part of this is just the sloppiness of which the mental health
profession has been accused for years and part is from the time constraints of managed care in
which the patient gets 30 minutes to make the diagnosis. When the examiner will only be
reimbursed for 30 minutes there is the short sighted tendency to cut corners.if the patient says "I'm
depressed" they go on an antidepressant usually without taking the really close history that it takes
to differentiate subtly different conditions.
2. the fact that most training programs not, even now, offer any training on ADHD at any age,
and
3. that we tend to recognize the things that we already know and, hence, see mood disorders
with which we feel comfortable when it really might be ADHD (about which most physicians are
functionally illiterate. Here we see the misuse of the terms "NOS" and "variant" when people really
mean that they can't shoe horn what they hear from the patient into the convenient boxes they
picked up in their residencies.
Four conditions must be distinguished from one another and from any
combination of the four.
1. ADHD
2. Bipolar Mood Disorder and its "variants"
3. Borderline Personality Disorder
4. Premenstrual Dysphoric Disorder
Overlap of symptoms is built into our nomenclature. The DSM IV has 295 separately named
conditions but only 167 symptoms. Consequently, it is often difficult to tease apart clinical histories
to arrive at an accurate diagnosis or set of co-existing conditions. Many psychiatric patients do not
have just one disorder. In a study of adults at the time they were diagnosed with ADHD it was
found that 41 per cent had another active axis I disorder. Thirty-eight percent, in other words
virtually all of that 41 percent, had two or more active axis I diagnoses. Coexisting conditions are
common and a thorough history must be taken during the initial evaluation to screen for a wide
variety of conditions.
To complicate accurate diagnosis even more, John Ratey points out that the vast majority of people
with ADHD have what he unfortunately called dyslexithymia. If you're at Harvard you have to put
things into Greek rather than saying that people with ADHD "use the wrong words for feelings."
My patients do not use words in the same way that I do and I have to take pains to slow down,
listen, and explore each person's unique use of words to describe abstract things like emotional
states. For instance, I suspect that the reported co-morbidity of ADHD and anxiety disorders is a
gross exaggeration. To be sure, about 40% of my adult ADHD patients come in reporting
"anxiety." When I ask them, however, to tell me more about their "baseless apprehensive fear" I
From @mail correpondance Dr Anderson & Dr Dodson (2007)
p 1 of4
usually get a very confused response."I never said I was afraid." More probing commonly brings
out that they are describing a lifelong state in which they are always tense, driven, can't slow down,
can't relax, and have a constant worry that they've missed or forgotten something. This is the
description of the somatic experience of hyperactivity not anxiety. A good portion of the initial
therapy sessions is my trying to understand how this unique individual uses language to describe
and get a handle on his or her emotional life. Poor communication leads to inaccurate diagnosis
which leads in turn to incorrect and ineffective treatment.
Adults with ADHD report that emotional instability is perhaps their most disruptive and impairing
symptom. The second most commonly endorsed feature on our adult ADHD checklist states "For
your entire life have you been much more sensitive than other people you know to rejection teasing,
criticism and frustration." This definition was lifted from the old Psychiatric Glossary term of
"rejection sensitive dysphoria." Fully 98 percent of adults with ADHD report exquisite sensitivity
to the perception of rejection, criticism, and teasing. This catastrophic emotional reaction is
often internalized with an instantaneous full depressive syndrome complete with suicidal ideation.
Many adults describe a physical stabbing pain in the chest. Other adults externalize the dysphoria in
fits of uncontrollable verbal rage at the person or thing that wounded them or that they perceive to
be the source of the rejection or humiliation. The interpersonal nature of the trigger and the sudden
overpowering of Ego defenses often lead to a mis diagnosis of borderline personality disorder
(BPD). Unfortunately, it usually takes extensive experience with a given patient to fully catalog the
presence or absence of the ego structures and object relations necessary to distinguish ADHD from
BPD and from the two conditions together.
Historically treatment has focused on the similarity of this mood lability with this much older
concept of rejection sensitive (or hysteroid) dysphoria. Although nothing has been published in the
last 15 years on these dysphorias, Wender originally used the MAO-I's --with fairly good results. In
an unpublished report of 227 adults with ADHD and severe rejection sensitivity all the patients
reported significant improvement in mood stability and rejection sensitivity while taking (which
has significant inhibition of monamine oxidase B as one of its many neurochemical activities). It is
unknown whether similar results will be obtained with methylphenidate.
Women with ADHD appear to have premenstrual disorder (PMS, Premenstrual Dysphoric Disorder)
more frequently and more severely then do women who do not have ADHD. Research protocols
currently require four out of five of the following criteria for a diagnosis of ADHD associated with
PMS:
highly regular and predictable menstrual cycle
highly predictable onset of dysphoric symptoms (ex. Always X number of days prior to menstrual
flow)
abrupt onset of dysphoric symptoms (the slang calls it a "ping")
abrupt offset of dysphoric symptoms
offset of symptoms simultaneous with the beginning of menstrual flow
Many women with co morbid PMS find it impossible to adjust stimulant class medications or report
that the medications don't work at all during their premenstrual time. Patricia Quinn knows more
about this than anyone else. Her thought is that the mood lability and lack of medication efficacy
have the same cause .low estrogen .since getting the estrogen level back up above 150 pg/ml
relieves all of these symptoms
From @mail correpondance Dr Anderson & Dr Dodson (2007)
p 2 of4
ADHD and BMD share 14 features in common and the recent National Co morbidity Survey
Replication found that 19% of adults with ADHD also met DSM IV criteria for BMD. There is
considerable co morbid overlap of the two disorders.
Research by Wilens et al. at Harvard has shown that the two conditions cannot be separated
accurately on the basis of the ADHD symptom set alone. It is the diagnostic criteria for cyclic mood
disorders that separate ADHD from Bipolar.only bipolar looks like bipolar. By diagnostic
definition the moods of a mood disorder "come out of the blue" without a triggering event
and "have taken on a life of their own, separate from the events of a person's life and out side
of their conscious will and control." The mood shifts are gradual.
Rapid cycling BMD is defined as
> 4 shifts in a 12 month period. Even ultra-rapid cycling bipolars take hours to days for their
moods to shift completely. Unlike people with ADHD, rapid cyclers are usually in a mixed state
and are profoundly impaired by their mood dyscontrol.
In contrast, most people with ADHD do not recall any episodes of mood that were
untriggered. In virtually every case there was .
1. a proximate trigger,
2. the mood matched the trigger (mood congruence), and
3. the mood shift was instantaneous.
In other words, the mood shifts were normal in every way except intensity. This is completely
consistent with ADHD alone and NOT with the comorbidity of ADHD plus Bipolar Mood Disorder.
Nonetheless, ADHD and bipolar mood disorder can be distinguished from one another on the basis
of six factors:
1) Age of onset: ADHD symptoms are usually evident early in childhood
and are consistently present lifelong. While BMD can be present in
prepubertal children the mean age at diagnosis in the U.S. is 26 years
of age (although it is common in hindsight to see mood instability
back to latte adolescence).
2) Consistency of impairment and symptoms: ADHD is always present.
BMD comes in episodes that ultimately remit to more or less normal,
euthymic mood levels commonly during the summer months in the Northern
hemisphere.
3) Triggered mood instability: People with ADHD are
passionate people who have strong emotional reactions to the events of
their lives. It is precisely this clear triggering of mood shifts,
however, that
distinguishes ADHD from the mood shifts of BMD that come and go
without any connection to life events.
4) Rapidity of mood shifts: The mood shifts of ADHD are triggered and
are almost always experienced as being instantaneous complete shifts
from one state to another. Typically, they are described as "crashes"
From @mail correpondance Dr Anderson & Dr Dodson (2007)
p 3 of4
or "snaps" which emphasize this sudden quality. By contrast, the
untriggered mood shifts of BMD take hours or days to move from one
state to another. The rapid cycling designation requires only four
shifts of mood in a 12 month period.
5) Duration of mood shifts: People with ADHD report that their moods
shift rapidly according to what's going on their lives. The response
to severe losses and rejections may last weeks but typically is much
shorter and is usually measured in hours. The mood shifts of BMD are
usually sustained and the DSM requires the abnormal mood to be
continuously present for more than two weeks in order to rise to a
mood disorder designation. For instance, to get the designation of a
rapid cycling bipolar disorder the person need only experience four
mood shifts from high to low or low to high in a twelve-month period
of time. Many persons with ADHD experience that many mood shifts in a
single day.
6) Family history: Both disorders run and families but people with BMD
usually have a family history of BMD while individuals with ADHD have
a family tree with multiple cases of ADHD........
This may be a lot more than you wanted but it really is this
complicated. I hope that you find it helpful in what seems like a very
long process of figuring out your life and why it has been so hard.
Warm regards,
Bill Dodson, M.D.
William W. Dodson, M.D.
Board Certified in Psychiatry
Specializing in Adult ADHD
Colorado
From @mail correpondance Dr Anderson & Dr Dodson (2007)
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