Latency can be caused by a number of things - geography, startup time, size of payload, etc. You can visit this blog on
How to Troubleshoot Latency in your App Engine Application and hopefully might help you isolate the latency problem.
It is also helpful to observe how long request takes to respond through
Stackdriver Trace. If this is not possible because most of the requests timeout, one should try to make split up or defer the work being done to respond to the request.
If you are still affected after trying the above, I recommend you post on
StackOverflow which we also monitor. You'll be in touch with a much larger user-base of people who are going to help you, in a format which is designed for that purpose. Check out our community support page for the list of tags we monitor.