Hi,
Thanks for your answer. I finaly found the issue. With Unity ads mediation you don't have to initialize Unity, its an automated process, so by initializing Unity ads in my code, the create the issue.
I delete this part of code, then the event onInterstitalAdClosed is triggered and everything work fine now.
I want to clarify something from you answer, you told me
"I would like to point out that the message you described should only
show when another Ad Request for an Interstitial Ad is still pending and
has not yet received a response. Judging from your code snippet and
your logs, it seems like this is the case. It is also possible that the
Ad Request returned an error."
But I think I avoid this by using "IsInterstisialsAdReady" need to be true to display an ads. And this become true only when an ad successfully loaded (by the event onInterstitalAdLoaded )
Thanks !