For my Go programs, I wrote a little library for Numbers that can be compile-time configured as native int64, multi-word but fixed precision, or unlimited precision using the math/big library. I have the math in assembler for the multiword cases. Generally the sizes needed are 2 to 5 ganged 64-bit words.
The resulting overall application speed is about 3x big for add/subtract, often more, though the advantage declines as the sizes get longer and longer or when the operations (divide, say) are much more complex. The actual operations are faster than this, though, given the large number of shared instructions for general tasks (loop management, tests).
I also wrote doubled precision (quad precision not finished) for floating point math. This uses two float64's and some judicious manipulations to get bit-exact representations of nearly doubled precision at about 1/4 the speed.
=== RUN TestPower
0: 3** 0 = 3ff0000000000000 0000000000000000, +1.0000000000000000e+00 +0.0000000000000000e+00 +1.0000000000000000000000000000000e+00
1: 3** 1 = 4008000000000000 0000000000000000, +3.0000000000000000e+00 +0.0000000000000000e+00 +3.0000000000000000000000000000000e+00
2: 3** 2 = 4022000000000000 0000000000000000, +9.0000000000000000e+00 +0.0000000000000000e+00 +9.0000000000000000000000000000000e+00
3: 3** 3 = 403b000000000000 0000000000000000, +2.7000000000000000e+01 +0.0000000000000000e+00 +2.7000000000000000000000000000000e+01
4: 3** 4 = 4054400000000000 0000000000000000, +8.1000000000000000e+01 +0.0000000000000000e+00 +8.1000000000000000000000000000000e+01
5: 3** 5 = 406e600000000000 0000000000000000, +2.4300000000000000e+02 +0.0000000000000000e+00 +2.4300000000000000000000000000000e+02
6: 3** 6 = 4086c80000000000 0000000000000000, +7.2900000000000000e+02 +0.0000000000000000e+00 +7.2900000000000000000000000000000e+02
7: 3** 7 = 40a1160000000000 0000000000000000, +2.1870000000000000e+03 +0.0000000000000000e+00 +2.1870000000000000000000000000000e+03
8: 3** 8 = 40b9a10000000000 0000000000000000, +6.5610000000000000e+03 +0.0000000000000000e+00 +6.5610000000000000000000000000000e+03
9: 3** 9 = 40d338c000000000 0000000000000000, +1.9683000000000000e+04 +0.0000000000000000e+00 +1.9683000000000000000000000000000e+04
10: 3** 10 = 40ecd52000000000 0000000000000000, +5.9049000000000000e+04 +0.0000000000000000e+00 +5.9049000000000000000000000000000e+04
11: 3** 11 = 41059fd800000000 0000000000000000, +1.7714700000000000e+05 +0.0000000000000000e+00 +1.7714700000000000000000000000000e+05
12: 3** 12 = 412037e200000000 0000000000000000, +5.3144100000000000e+05 +0.0000000000000000e+00 +5.3144100000000000000000000000000e+05
13: 3** 13 = 413853d300000000 0000000000000000, +1.5943230000000000e+06 +0.0000000000000000e+00 +1.5943230000000000000000000000000e+06
14: 3** 14 = 41523ede40000000 0000000000000000, +4.7829690000000000e+06 +0.0000000000000000e+00 +4.7829690000000000000000000000000e+06
15: 3** 15 = 416b5e4d60000000 0000000000000000, +1.4348907000000000e+07 +0.0000000000000000e+00 +1.4348907000000000000000000000000e+07
16: 3** 16 = 418486ba08000000 0000000000000000, +4.3046721000000000e+07 +0.0000000000000000e+00 +4.3046721000000000000000000000000e+07
17: 3** 17 = 419eca170c000000 0000000000000000, +1.2914016300000000e+08 +0.0000000000000000e+00 +1.2914016300000000000000000000000e+08
18: 3** 18 = 41b7179149000000 0000000000000000, +3.8742048900000000e+08 +0.0000000000000000e+00 +3.8742048900000000000000000000000e+08
19: 3** 19 = 41d151acf6c00000 0000000000000000, +1.1622614670000000e+09 +0.0000000000000000e+00 +1.1622614670000000000000000000000e+09
20: 3** 20 = 41e9fa8372200000 0000000000000000, +3.4867844010000000e+09 +0.0000000000000000e+00 +3.4867844010000000000000000000000e+09
21: 3** 21 = 42037be295980000 0000000000000000, +1.0460353203000000e+10 +0.0000000000000000e+00 +1.0460353203000000000000000000000e+10
22: 3** 22 = 421d39d3e0640000 0000000000000000, +3.1381059609000000e+10 +0.0000000000000000e+00 +3.1381059609000000000000000000000e+10
23: 3** 23 = 4235eb5ee84b0000 0000000000000000, +9.4143178827000000e+10 +0.0000000000000000e+00 +9.4143178827000000000000000000000e+10
24: 3** 24 = 425070872e384000 0000000000000000, +2.8242953648100000e+11 +0.0000000000000000e+00 +2.8242953648100000000000000000000e+11
25: 3** 25 = 4268a8cac5546000 0000000000000000, +8.4728860944300000e+11 +0.0000000000000000e+00 +8.4728860944300000000000000000000e+11
26: 3** 26 = 42827e9813ff4800 0000000000000000, +2.5418658283290000e+12 +0.0000000000000000e+00 +2.5418658283290000000000000000000e+12
27: 3** 27 = 429bbde41dfeec00 0000000000000000, +7.6255974849870000e+12 +0.0000000000000000e+00 +7.6255974849870000000000000000000e+12
28: 3** 28 = 42b4ce6b167f3100 0000000000000000, +2.2876792454961000e+13 +0.0000000000000000e+00 +2.2876792454961000000000000000000e+13
29: 3** 29 = 42cf35a0a1bec980 0000000000000000, +6.8630377364883000e+13 +0.0000000000000000e+00 +6.8630377364883000000000000000000e+13
30: 3** 30 = 42e76838794f1720 0000000000000000, +2.0589113209464900e+14 +0.0000000000000000e+00 +2.0589113209464900000000000000000e+14
31: 3** 31 = 43018e2a5afb5158 0000000000000000, +6.1767339628394700e+14 +0.0000000000000000e+00 +6.1767339628394700000000000000000e+14
32: 3** 32 = 431a553f8878fa04 0000000000000000, +1.8530201888518410e+15 +0.0000000000000000e+00 +1.8530201888518410000000000000000e+15
33: 3** 33 = 4333bfefa65abb83 0000000000000000, +5.5590605665555230e+15 +0.0000000000000000e+00 +5.5590605665555230000000000000000e+15
34: 3** 34 = 434d9fe779881944 3ff0000000000000, +1.6677181699666568e+16 +1.0000000000000000e+00 +1.6677181699666569000000000000000e+16
35: 3** 35 = 436637ed9b2612f3 4008000000000000, +5.0031545098999704e+16 +3.0000000000000000e+00 +5.0031545098999707000000000000000e+16
36: 3** 36 = 4380a9f2345c8e37 c02e000000000000, +1.5009463529699914e+17 -1.5000000000000000e+01 +1.5009463529699912100000000000000e+17
37: 3** 37 = 4398feeb4e8ad552 c02a000000000000, +4.5028390589099738e+17 -1.3000000000000000e+01 +4.5028390589099736300000000000000e+17
38: 3** 38 = 43b2bf307ae81ffd 4056400000000000, +1.3508517176729920e+18 +8.9000000000000000e+01 +1.3508517176729920890000000000000e+18
39: 3** 39 = 43cc1ec8b85c2ffc 4026000000000000, +4.0525551530189763e+18 +1.1000000000000000e+01 +4.0525551530189762670000000000000e+18
40: 3** 40 = 43e517168a4523fd 4040800000000000, +1.2157665459056929e+19 +3.3000000000000000e+01 +1.2157665459056928801000000000000e+19
41: 3** 41 = 43ffa2a1cf67b5fc c09e740000000000, +3.6472996377170788e+19 -1.9490000000000000e+03 +3.6472996377170786403000000000000e+19
42: 3** 42 = 4417b9f95b8dc87d c0b6d70000000000, +1.0941898913151237e+20 -5.8470000000000000e+03 +1.0941898913151235920900000000000e+20
43: 3** 43 = 4431cb7b04aa565d 40dedec000000000, +3.2825696739453705e+20 +3.1611000000000000e+04 +3.2825696739453707762700000000000e+20
44: 3** 44 = 444ab13886ff818c 40dc9c4000000000, +9.8477090218361120e+20 +2.9297000000000000e+04 +9.8477090218361123288100000000000e+20
45: 3** 45 = 446404ea653fa129 40f5753000000000, +2.9543127065508336e+21 +8.7891000000000000e+04 +2.9543127065508336986430000000000e+21
46: 3** 46 = 447e075f97df71be c10fd03800000000, +8.8629381196525014e+21 -2.6061500000000000e+05 +8.8629381196525010959290000000000e+21
47: 3** 47 = 44968587b1e7954e 413411eb00000000, +2.6588814358957502e+22 +1.3153070000000000e+06 +2.6588814358957503287787000000000e+22
48: 3** 48 = 44b0e425c56daffb c150f28fc0000000, +7.9766443076872514e+22 -4.4426870000000000e+06 +7.9766443076872509863361000000000e+22
49: 3** 49 = 44c95638a82487f8 414a50a180000000, +2.3929932923061753e+23 +3.4491550000000000e+06 +2.3929932923061752959008300000000e+23
50: 3** 50 = 44e300aa7e1b65fa 4163bc7920000000, +7.1789798769185258e+23 +1.0347465000000000e+07 +7.1789798769185258877024900000000e+23
51: 3** 51 = 44fc80ffbd2918f7 417d9ab5b0000000, +2.1536939630755577e+24 +3.1042395000000000e+07 +2.1536939630755577663107470000000e+24
52: 3** 52 = 451560bfcdded2b9 41b58d0211000000, +6.4610818892266729e+24 +3.6156264100000000e+08 +6.4610818892266732989322410000000e+24
53: 3** 53 = 4530088fda671e0b 4164e0c660000000, +1.9383245667680020e+25 +1.0946099000000000e+07 +1.9383245667680019896796723000000e+25
54: 3** 54 = 45480cd7c79aad11 c1efc15dace00000, +5.8149737003040064e+25 -4.2621289990000000e+09 +5.8149737003040059690390169000000e+25
55: 3** 55 = 456209a1d5b401cc 42082ef9be580000, +1.7444921100912017e+26 +1.2983416779000000e+10 +1.7444921100912017907117050700000e+26
56: 3** 56 = 457b0e72c08e02b3 c21bb989627c0000, +5.2334763302736057e+26 -2.9769226399000000e+10 +5.2334763302736053721351152100000e+26
57: 3** 57 = 45944ad6106a8206 c2132c9c27740000, +1.5700428990820816e+27 -2.0588202461000000e+10 +1.5700428990820816116405345630000e+27
58: 3** 58 = 45ae7041189fc309 c22cc2ea3b2e0000, +4.7101286972462449e+27 -6.1764607383000000e+10 +4.7101286972462448349216036890000e+27
59: 3** 59 = 45c6d430d277d247 c265648beb18a000, +1.4130386091738735e+28 -7.3504963603700000e+11 +1.4130386091738734504764811067000e+28
60: 3** 60 = 45e11f249dd9ddb5 c1f6d1e0a4f00000, +4.2391158275216204e+28 -6.1256525590000000e+09 +4.2391158275216203514294433201000e+28
61: 3** 61 = 45f9aeb6ecc6cc8f 429feee297844c00, +1.2717347482564860e+29 +8.7777160645310000e+12 +1.2717347482564861054288329960300e+29
62: 3** 62 = 461343093195196c c2b80cd60e5cc700, +3.8152042447694586e+29 -2.6443409939655000e+13 +3.8152042447694583162864989880900e+29
63: 3** 63 = 462ce48dca5fa621 42cbecbeea74d580, +1.1445612734308374e+30 +6.1407258536363000e+13 +1.1445612734308374948859496964270e+30
64: 3** 64 = 4645ab6a57c7bc99 42c3c63cbf5e8080, +3.4336838202925124e+30 +4.3484287253761000e+13 +3.4336838202925124846578490892810e+30
65: 3** 65 = 4660408fc1d5cd73 c2f895a9383c8fd0, +1.0301051460877538e+31 -4.3249709166002900e+14 +1.0301051460877537453973547267843e+31
--- PASS: TestPower (0.00 seconds)