Brother, you are thinking in the right direction but trust me as you will see-- all of those wheels have been turned:
I looked at using a 4wd truck chassis-- the driving position was totally in the wrong place. The modifications needed to put the wheels and the driver where they must be was so close to impossible that the mods to do it would be insane.
Then, I looked at an enginnered complete chassis and found the at that time LF-72 Workhorse airport shuttle bus chassis. It was a Duramax turbo diesel, Allison 1000 5 speed trans connected to a heavy duty German transfer case fed to a solid front axle. All air bag susupension, OBDII, ABS brakes, a 22,000 GVW "X" frame chassic with 1.95" rims, all wheel disc brakes that look like they came off the shuttle. Again, the driving position was @ 15" back. We brought the position up 8" (max possible) which made us modify the window compliment-- top deck driver platfor and all the interior back to the entry door.
The entire body of both a 23' and 26' coach were both plopped up on this chassis complete with a full ground effects package. Cost on the modestly outfitted 23' conversion topped $250,000 and the detailed and awesome 26' coach cost over $400,000 to complete and it's still not done to the actors satisfaction which he plans to finish.
As you can see, there is no real way to do projects like these on a low budget and have them a viable, reliable, maintainable travel vehicle. The ending floorplans were not that user friendly, they worked but similar to the "Spruce Goose" it was not practical.
It's fun to squeeze these creative juices into a glass just be sure you don;t choke on trying to drink the concoction! I did, you have to go there to find where "too far" is, I've been there, have the shirt and won't do it again.
Jim Bounds
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