Something to think about: Some states are now implementing checks for tire age. For example, in Oregon, if a truck or motorhome is stopped for anything, or in an accident, the SP probably will check the age of the tires. If the date code makes them more than 7 years old, there is a deep fine. 7 years is the recommended max age for a tire carcass now.
Since you will have to replace your tires in 7 years, a) make sure you are purchasing fresh tires when you buy new ones. b) consider if you want to pay for the best ones out there, then throw them out with full tread left after 7 years (You will probably never wear them out in that time). c) Consider where you could get a guarantee honored when you are on the road, away from home.
Finally, check the load rating, keep them air'd to the recommended pressure, and get only LT tires, not P.
All in all, motels are cheaper... :d