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Analisa Wack

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Aug 4, 2024, 9:58:29 PM8/4/24
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Thisguidance is intended for people who have had mpox exposures in the community. Guidance for exposures in healthcare settings can be found here: Infection Prevention and Control of Mpox in Healthcare Settings.

Anyone with an exposure to people or animals with mpox should monitor their health or be monitored for signs or symptoms consistent with mpox for 21 days after their last exposure. Information about human-to-human transmission of monkeypox virus is described in How it Spreads Mpox Poxvirus CDC.


Monitoring should include assessing the person for signs and symptoms of mpox, including a thorough skin and mouth (oral) exam in good lighting. Skin examination can be performed by the person in isolation, a caregiver, or a healthcare provider and should include examination of the genitals and anus for rash or lesions.


To date, there have been no cases of mpox transmitted by blood transfusion, organ transplantation, or implantation, transplantation, infusion, or transfer of human cells, tissues, or cellular or tissue-based products (HCT/Ps). As a precaution, patients with exposures should not donate blood, cells, tissue, breast milk, or semen while they are being monitored for symptoms. Given the morbidity and mortality among individuals awaiting organ transplantation, persons who have been exposed, but who are asymptomatic and without evidence of monkeypox virus infection, could be considered for organ donation following appropriate risk-benefit considerations.


Some people may be unable to communicate onset of symptoms, such as newborns, young children, or people with cognitive disorders. Parents and other caregivers should watch for changes in behavior and temperament that could signal that the person is experiencing uncomfortable symptoms such as fatigue or headache.


Each risk level category in the table below is intended to highlight the need for monitoring and assist with determining the need for postexposure prophylaxis (PEP). The exposure risk level of any incident may be recategorized to another risk level at the discretion of the treating clinician or public health authorities due to the unique circumstances of each exposure incident.


Mpox typically spreads through prolonged close, skin-to-skin contact with a person who has mpox, or their contaminated materials (e.g., clothing, bed sheets). Transmission during quick interactions (e.g., brief conversation), between people in close proximity has not been reported for any persons with mpox.


There may be settings in which contact tracing is not feasible due to the characteristics of the setting (e.g., level of crowding, types of interactions occurring). In settings where contact tracing is not feasible, people who spent time in the same area as someone with mpox should be considered to have intermediate or lower degree of exposure.


Factors that may increase the risk of mpox transmission include (but are not limited to): the person with mpox had clothes that were soiled with bodily fluids or secretions (e.g., discharge, skin lesion crusts or scabs on clothes) or was coughing while not wearing a mask or respirator, or the exposed individual is not previously vaccinated against smallpox or mpox. People who may be at increased risk for severe disease include (but are not limited to): young children (


The Monitoring Coalition Program is a voluntary, ambient monitoring program that provides an effective and efficient means for assessing water quality in a watershed context. A monitoring coalition is a group of stakeholders that combine resources and expertise, to collectively fund and perform an in-stream monitoring program. If any members of the monitoring coalitions are NPDES wastewater or drinking water permit holders, the monitoring performed by this Program can be done in lieu of the in-stream monitoring required by their individual permits.

By forming a coalition, members have a medium to gather more information about their watersheds, evaluate member-specific interests and collaborate on watershed specific issues. Coalition members work with DWR to develop a monitoring network that uses strategically selected, mutually agreeable sampling locations to evaluate water quality beyond the point-source outfall. The monitoring locations are coordinated with the State's existing ambient and biological monitoring networks, to provide a more comprehensive picture of watershed conditions without duplicating efforts.


Since February 1996, the Lower Cape Fear River Program has monitored from Lock and Dam 1 down to Southport. Thirty-one stations are currently monitored on a monthly basis. Details of the current monitoring program can be found in the Memorandum of Agreement. The LCFRP has supported research at UNC-Wilmington in a variety of water quality studies. Currently the members are working with DWR on the development of a Total Maximum Daily Load (TMDL) for the Cape Fear Estuary.


The members of the Lower Neuse Basin Association have monitored the Neuse River basin downstream of Falls Lake since December 1994. Currently the LNBA monitors 55 stations monthly. Details of this monitoring program can be found in the Memorandum of Agreement. The association, in cooperation with the Neuse River Compliance Association (NRCA), has actively supported nutrient management within the basin through upgrades to nutrient removal systems at member wastewater treatment facilities, and has provided financial assistance to academic researcher on nutrient loading. The Association is working with DWR and academia, to evaluate the effectiveness of the TMDL in reducing the nitrogen load to the Neuse estuary.


Since July 1998, the Middle Cape Fear River Basin Association has monitored from the confluence of the Haw and Deep Rivers to Lock and Dam 1. Today the association monitors 36 stations monthly. Details of the monitoring plan can be found in the association's Memorandum of Agreement. The MCFRBA has helped expand water quality knowledge within the river basin, by supporting academic research and conducting studies on fecal coliform and low level metals.


The Tar-Pamlico Basin Association has monitored the basin since March 2007. The Association currently collects monthly data at 37 stations. Details of the monitoring plan can be found in the Memorandum of Agreement. The TPBA has worked cooperatively with DWQ to comply with the Tar-Pamlico Nutrient Strategy and is preparing for Phase IV negotiations.


The Upper Cape Fear River Basin Association has monitored the waters of the Cape Fear River Basin from the headwaters to the confluence of the Haw and Deep Rivers since April 2000. The group currently monitors 40 stations monthly. Details of the monitoring plan can be found in the Memorandum of Agreement. The association has worked with the US Geological Society (USGS) to study sediment and nutrients within the watershed. Members were also active in the development of the Jordan Lake TMDL.


The Yadkin/Pee Dee River Basin Association has monitored the Yadkin basin from the headwaters to the South Carolina border, since June 1998. The association currently monitors 71 stations monthly. Details on the monitoring program can be found in the Memorandum of Agreement. Association members have also supported water quality improvement efforts within the basin through stream restoration projects and participation in watershed planning. Currently the association is working with DWR and other stakeholders in the development of a Total Maximum Daily Load (TMDL) for High Rock Lake.


EPA uses the Unregulated Contaminant Monitoring Rule (UCMR) to collect data for contaminants that are suspected to be present in drinking water and do not have health-based standards set under the Safe Drinking Water Act (SDWA).


In establishing the list of contaminants for each UCMR cycle, EPA considers the CCL and other priority contaminants. Further, EPA considered the opportunity to use multi-contaminant methods to collect occurrence data in an efficient, cost-effective manner.


EPA evaluates candidate UCMR contaminants using a multi-step prioritization process. The first step includes identifying contaminants that: (1) were not monitored under prior UCMR cycles; (2) may occur in drinking water; and (3) are expected to have a completed, validated drinking water method in time for rule proposal.


The next step is to consider the following: availability of health assessments or other health-effects information (e.g., critical health endpoints suggesting carcinogenicity); public interest (e.g., PFAS); active use (e.g., pesticides that are registered for use); and availability of occurrence data.


During the final step, EPA considers stakeholder input; looks at cost-effectiveness of the potential monitoring approaches; considers implementation factors (e.g., laboratory capacity); and further evaluates health effects, occurrence, and persistence/mobility data to identify the list of proposed UCMR contaminants.


UCMR provides EPA and others with scientifically valid data on the occurrence of these contaminants in drinking water. This permits assessment of the population being exposed and the levels of exposure.


UCMR data represent one of the primary sources of national occurrence data in drinking water that EPA uses to inform regulatory and other risk management decisions for drinking water contaminants. This data will ensure science-based decision-making and help prioritize protection of disadvantaged communities.


Ultimately, the framework creates a flexible, yet consistent, monitoring and evaluation approach. This approach will help us determine if a project is successful, improve the effectiveness of our work, and measure progress towards our desired program outcomes. The details outlined below demonstrate how the Community-based Restoration Program implements the framework.


Implementation monitoring allows us to evaluate whether a project was executed as designed. It is required for all project types shortly after implementation is complete. Implementation monitoring is essentially quality assurance for project construction.

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