If you're asking for help, you must post a log to receive any useful guidance. Instructions for producing a log are here: -retroarch-logs/ Please copy your log to somewhere like pastebin.com and then include a link in your post.
If a custom installation directory is used for RetroArch, shims will still be created for retroarch.exe and retroarch_debug.exe on the path so that RetroArch can be started from the command line as with prior versions of this package.